Establishment and Validation of Whole-Cell Based Fluorescence Assays to Identify Anti-Mycobacterial Compounds Using the Acanthamoeba castellanii - Mycobacterium marinum Host-Pathogen System

Integration of Chemical and RNAi Multiparametric Profiles Identifies Triggers of Intracellular Mycobacterial Killing

(2013) Varadharajan Sundaramurthy et al.   Cell Host & Microbe

Mycobacterium canettii is intrinsically resistant to both pyrazinamide and pyrazinoic acid

(2013) S. Feuerriegel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish

(2013) Kevin Takaki et al.   Nature Protocols

A Dual Read-Out Assay to Evaluate the Potency of Compounds Active against Mycobacterium tuberculosis

(2013) Juliane Ollinger et al.   PLoS One

Conserved Mechanisms of Mycobacterium marinum Pathogenesis within the Environmental Amoeba Acanthamoeba castellanii

(2012) George M. Kennedy et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

TheLegionella pneumophilaorphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit

(2012) Aline Kessler et al.   ENVIRONMENTAL MICROBIOLOGY

Mycobacterium marinum infection in Drosophila melanogaster for antimycobacterial activity assessment

(2012) C.-T. Oh et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A new in vivo model to test anti-tuberculosis drugs using fluorescence imaging

(2012) A. Zelmer et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence

(2012) Rachel E. Butler et al.   PLoS One

The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis

(2012) Borna Müller et al.   TRENDS IN GENETICS

An In Vivo Platform for Rapid High-Throughput Antitubercular Drug Discovery

(2012) Kevin Takaki et al.   Cell Reports

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

Role of Rifampin-Based Combination Therapy for Severe Community-Acquired Legionella pneumophila Pneumonia

(2011) Terra R Varner et al.   ANNALS OF PHARMACOTHERAPY

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

(2011) Laeticia Alibaud et al.   MOLECULAR MICROBIOLOGY

A High-Throughput Screen for Tuberculosis Progression

(2011) Ralph Carvalho et al.   PLoS One

Inside or outside the phagosome? The controversy of the intracellular localization of Mycobacterium tuberculosis

(2011) Amanda Welin et al.   TUBERCULOSIS

Legionellaspp. outdoors: colonization, communication and persistence

(2011) Hubert Hilbi et al.   Environmental Microbiology Reports

Genome-wide Analysis of the Host Intracellular Network that Regulates Survival of Mycobacterium tuberculosis

(2010) Dhiraj Kumar et al.   CELL

Evolution of Pseudomonas aeruginosa virulence in infected patients revealed in a Dictyostelium discoideum host model

(2010) E. Lelong et al.   CLINICAL MICROBIOLOGY AND INFECTION

Novel agents to inhibit microbial virulence and pathogenicity

(2010) Sonia Escaich   EXPERT OPINION ON THERAPEUTIC PATENTS

High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery

(2010) Thierry Christophe et al.   Future Medicinal Chemistry

Identification of Host-Dependent Survival Factors for Intracellular Mycobacterium tuberculosis through an siRNA Screen

(2010) Shilpi Jayaswal et al.   PLoS Pathogens

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

(2009) J. Muse Davis et al.   CELL

Free-living amoebae, a training field for macrophage resistance of mycobacteria

(2009) I.B. Salah et al.   CLINICAL MICROBIOLOGY AND INFECTION

Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis

(2009) Pooja Arora et al.   Nature Chemical Biology

Dictyostelium discoideum: a model host to measure bacterial virulence

(2009) Romain Froquet et al.   Nature Protocols

Infection by Tubercular Mycobacteria Is Spread by Nonlytic Ejection from Their Amoeba Hosts

(2009) M. Hagedorn et al.   SCIENCE

Discovery and validation of new antitubercular compounds as potential drug leads and probes

(2009) Robert C. Goldman et al.   TUBERCULOSIS

Selectivity of TMC207 towards Mycobacterial ATP Synthase Compared with That towards the Eukaryotic Homologue

(2008) A. C. Haagsma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Promising Antituberculosis Activity of the Oxazolidinone PNU-100480 Relative to That of Linezolid in a Murine Model

(2008) K. N. Williams et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A New Antituberculosis Drug that Selectively Kills Nonmultiplying Mycobacterium tuberculosis

(2008) Denis A. Mitchison   Cell Host & Microbe

Eat, kill or die: when amoeba meets bacteria

(2008) Pierre Cosson et al.   CURRENT OPINION IN MICROBIOLOGY

A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents

(2008) J. G. Hurdle et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Synthesis and antitubercular activity of a series of hydrazone and nitrovinyl analogs derived from heterocyclic aldehydes

(2008) Vijayakumar N. Sonar et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Bovine TB: don't get rid of the cat because the mice have gone

(2008) Noel H. Smith et al.   NATURE

PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release

(2008) R. Singh et al.   SCIENCE