Histone Deacetylase Inhibitors Selectively Target Homology Dependent DNA Repair Defective Cells and Elevate Non-Homologous Endjoining Activity

FANCM and FAAP24 Maintain Genome Stability via Cooperative as Well as Unique Functions

(2013) Yucai Wang et al.   MOLECULAR CELL

Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase

(2013) E. M. Kass et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair

(2013) K.-Y. Hsiao et al.   Journal of Molecular Cell Biology

Multi-Targeted Histone Deacetylase Inhibitors in Cancer Therapy

(2012) T. Ai et al.   CURRENT MEDICINAL CHEMISTRY

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction

(2012) Sehyun Oh et al.   NUCLEIC ACIDS RESEARCH

Homologous recombination and its regulation

(2012) L. Krejci et al.   NUCLEIC ACIDS RESEARCH

Loss of CCDC6, the First Identified RET Partner Gene, Affects pH2AX S139 Levels and Accelerates Mitotic Entry upon DNA Damage

(2012) Francesco Merolla et al.   PLoS One

High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death

(2012) J. T. Fox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prostate Cancer Cell Surface-Associated Keratin 8 and Its Implications for Enhanced Plasmin Activity

(2012) Melissa Hirsch Kuchma et al.   PROTEIN JOURNAL

DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity

(2011) Nilabja Sikdar et al.   CELL CYCLE

SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis

(2011) D Li et al.   CELL DEATH AND DIFFERENTIATION

HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: Existence of an alternative E3 ligase

(2011) Peter H.L. Krijger et al.   DNA REPAIR

Histone Deacetylases 9 and 10 Are Required for Homologous Recombination

(2011) Shweta Kotian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI

(2011) George-Lucian Moldovan et al.   MOLECULAR CELL

GADD45α inhibition of DNMT1 dependent DNA methylation during homology directed DNA repair

(2011) Bongyong Lee et al.   NUCLEIC ACIDS RESEARCH

DNA double-strand break repair pathways, chromosomal rearrangements and cancer

(2011) Torben R. Kasparek et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cancer cells’ epigenetic composition and predisposition to histone deacetylase inhibitor sensitization

(2011) Narasimharao Nalabothula et al.   Epigenomics

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Mutant cells defective in DNA repair pathways provide a sensitive high-throughput assay for genotoxicity

(2010) Terry John Evans et al.   DNA REPAIR

Human ELG1 Regulates the Level of Ubiquitinated Proliferating Cell Nuclear Antigen (PCNA) through Its Interactions with PCNA and USP1

(2010) Kyoo-young Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Methyltransferase 1-associated Protein (DMAP1) Is a Co-repressor That Stimulates DNA Methylation Globally and Locally at Sites of Double Strand Break Repair

(2010) Gun E. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair

(2010) J.- H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells

(2010) Farjana Fattah et al.   PLoS Genetics

FANCJ Uses Its Motor ATPase to Destabilize Protein-DNA Complexes, Unwind Triplexes, and Inhibit RAD51 Strand Exchange

(2009) Joshua A. Sommers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

(2008) Louise J. Barber et al.   CELL

Comparison of nonhomologous end joining and homologous recombination in human cells

(2008) Z MAO et al.   DNA REPAIR