Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction

Electron microscopy visualization of DNA–protein complexes formed by Ku and DNA ligase IV

(2011) Patricia Grob et al.   DNA REPAIR

Induction and repair of DNA double strand breaks: The increasing spectrum of non-homologous end joining pathways

(2011) Emil Mladenov et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

AAV-mediated gene targeting methods for human cells

(2011) Iram F Khan et al.   Nature Protocols

DNA repair deficiency in neurodegeneration

(2011) Dennis Kjølhede Jeppesen et al.   PROGRESS IN NEUROBIOLOGY

Ku Must Load Directly onto the Chromosome End in Order to Mediate Its Telomeric Functions

(2011) Christopher R. Lopez et al.   PLoS Genetics

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

(2011) Deniz Simsek et al.   PLoS Genetics

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory

(2010) Cynthia A. Massaad et al.   ANTIOXIDANTS & REDOX SIGNALING

Ku80 facilitates chromatin binding of the telomere binding protein, TRF2

(2010) Lauren S. Fink et al.   CELL CYCLE

The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres

(2010) Rekha Rai et al.   EMBO JOURNAL

TRF2/RAP1 and DNA–PK mediate a double protection against joining at telomeric ends

(2010) Oriane Bombarde et al.   EMBO JOURNAL

Collaboration and competition between DNA double-strand break repair pathways

(2010) Elizabeth M. Kass et al.   FEBS LETTERS

Mouse Embryonic Stem Cells, but Not Somatic Cells, Predominantly Use Homologous Recombination to Repair Double-Strand DNA Breaks

(2010) Elisia D. Tichy et al.   STEM CELLS AND DEVELOPMENT

Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells

(2010) Farjana Fattah et al.   PLoS Genetics

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

Telomere Dysfunction and DNA-PKcs Deficiency: Characterization and Consequence

(2009) E. S. Williams et al.   CANCER RESEARCH

DNA-PKcs deficiency in human: long predicted, finally found

(2009) Mirjam van der Burg et al.   Current Opinion in Allergy and Clinical Immunology

Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ

(2009) Susan J. Hsiao et al.   JOURNAL OF CELL BIOLOGY

Ku's essential role in keeping telomeres intact

(2009) S. M. Indiviglio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ku86 represses lethal telomere deletion events in human somatic cells

(2009) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Backup pathways of NHEJ in cells of higher eukaryotes: Cell cycle dependence

(2009) George Iliakis   RADIOTHERAPY AND ONCOLOGY

How Telomeres Solve the End-Protection Problem

(2009) T. de Lange   SCIENCE

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

DNA-damage repair; the good, the bad, and the ugly

(2008) Razqallah Hakem   EMBO JOURNAL

DNA damage and repair during lymphoid development: antigen receptor diversity, genomic integrity and lymphomagenesis

(2008) Nahum Puebla-Osorio et al.   IMMUNOLOGIC RESEARCH

Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV–deficient B cells

(2008) Li Han et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Catalytic Subunit of DNA-Dependent Protein Kinase Regulates Proliferation, Telomere Length, and Genomic Stability in Human Somatic Cells

(2008) B. L. Ruis et al.   MOLECULAR AND CELLULAR BIOLOGY

Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting

(2008) Susumu Iiizumi et al.   NUCLEIC ACIDS RESEARCH

Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic cells

(2008) F. J. Fattah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

(2008) Mitch McVey et al.   TRENDS IN GENETICS