HIV Rev Assembly on the Rev Response Element (RRE): A Structural Perspective

The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication

(2015) Chringma Sherpa et al.   NUCLEIC ACIDS RESEARCH

Long lasting control of viral rebound with a new drug ABX464 targeting Rev – mediated viral RNA biogenesis

(2015) Noëlie Campos et al.   Retrovirology

HIV-1 Rev Multimerization: Mechanism and Insights

(2014) Thomas Vercruysse et al.   CURRENT HIV RESEARCH

Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays

(2014) Joanna Sztuba-Solinska et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequence-based design of bioactive small molecules that target precursor microRNAs

(2014) Sai Pradeep Velagapudi et al.   Nature Chemical Biology

Gammaretrovirus mRNA expression is mediated by a novel, bipartite post-transcriptional regulatory element

(2014) Guy R. Pilkington et al.   NUCLEIC ACIDS RESEARCH

Functional Analyses Reveal Extensive RRE Plasticity in Primary HIV-1 Sequences Selected under Selective Pressure

(2014) Francesc Cunyat et al.   PLoS One

The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA

(2014) David S Booth et al.   eLife

RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev–Rev response element complex

(2014) Bhargavi Jayaraman et al.   eLife

RNA-guided assembly of Rev-RRE nuclear export complexes

(2014) Yun Bai et al.   eLife

Target-directed catalytic metallodrugs

(2013) J.C. Joyner et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

An Unusual Topological Structure of the HIV-1 Rev Response Element

(2013) Xianyang Fang et al.   CELL

Limited Nucleotide Changes in the Rev Response Element (RRE) during HIV-1 Infection Alter Overall Rev-RRE Activity and Rev Multimerization

(2013) E. A. Sloan et al.   JOURNAL OF VIROLOGY

The HIV-2 Rev-response element: determining secondary structure and defining folding intermediates

(2013) Sabrina Lusvarghi et al.   NUCLEIC ACIDS RESEARCH

In-gel probing of individual RNA conformers within a mixed population reveals a dimerization structural switch in the HIV-1 leader

(2013) Julia C. Kenyon et al.   NUCLEIC ACIDS RESEARCH

Targeting folded RNA: a branched peptideboronic acid that binds to a large surface area of HIV-1 RRE RNA

(2013) Wenyu Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Comparison of SIV and HIV-1 Genomic RNA Structures Reveals Impact of Sequence Evolution on Conserved and Non-Conserved Structural Motifs

(2013) Elizabeth Pollom et al.   PLoS Pathogens

Automated 3D structure composition for large RNAs

(2012) Mariusz Popenda et al.   NUCLEIC ACIDS RESEARCH

The HIV-1 Rev response element

(2012) Jason Fernandes et al.   RNA Biology

Toward Targeting RNA Structure: Branched Peptides as Cell-Permeable Ligands to TAR RNA

(2011) David I. Bryson et al.   ACS Chemical Biology

Interference of hepatitis C virus replication in cell culture by antisense peptide nucleic acids targeting the X-RNA

(2011) D.-G. Ahn et al.   JOURNAL OF VIRAL HEPATITIS

Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble

(2011) Andrew C Stelzer et al.   Nature Chemical Biology

Multiplexed RNA structure characterization with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

(2011) J. B. Lucks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for cooperative RNA binding and export complex assembly by HIV Rev

(2010) Matthew D Daugherty et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element

(2010) M. A. DiMattia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the HIV-1 Rev response element alone and in complex with regulator of virion (Rev) studied by atomic force microscopy

(2009) Jesper Pallesen et al.   FEBS Journal

Architecture and secondary structure of an entire HIV-1 RNA genome

(2009) Joseph M. Watts et al.   NATURE

HIV-1 Rev protein assembles on viral RNA one molecule at a time

(2009) S. J. K. Pond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Solution to Limited Genomic Capacity: Using Adaptable Binding Surfaces to Assemble the Functional HIV Rev Oligomer on RNA

(2008) Matthew D. Daugherty et al.   MOLECULAR CELL

Resistance to RevM10 inhibition reflects a conformational switch in the HIV-1 Rev response element

(2008) M. Legiewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein structure and oligomerization are important for the formation of export-competent HIV-1 Rev-RRE complexes

(2008) Stephen P. Edgcomb et al.   PROTEIN SCIENCE