Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble

RNA Dynamics by Design: Biasing Ensembles Towards the Ligand-Bound State

(2010) Andrew C. Stelzer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein

(2010) Amy Davidson et al.   NUCLEIC ACIDS RESEARCH

The Dynamic Landscapes of RNA Architecture

(2009) José Almeida Cruz et al.   CELL

RNA and Disease

(2009) Thomas A. Cooper et al.   CELL

Comparative Assessment of Scoring Functions on a Diverse Test Set

(2009) Tiejun Cheng et al.   Journal of Chemical Information and Modeling

NMR Chemical Exchange as a Probe for Ligand-Binding Kinetics in a Theophylline-Binding RNA Aptamer

(2009) Michael P. Latham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA

(2009) Jerod Parsons et al.   Nature Chemical Biology

Constructing RNA dynamical ensembles by combining MD and motionally decoupled NMR RDCs: new insights into RNA dynamics and adaptive ligand recognition

(2009) Aaron T. Frank et al.   NUCLEIC ACIDS RESEARCH

Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein

(2009) A. Davidson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DOCK 6: Combining techniques to model RNA-small molecule complexes

(2009) P. T. Lang et al.   RNA

Targeting RNA with Small Molecules

(2008) Jason R. Thomas et al.   CHEMICAL REVIEWS

Insight into the mechanisms of aminoglycoside derivatives interaction with HIV-1 entry steps and viral gene transcription

(2008) Aviva Lapidot et al.   FEBS Journal

Docking to RNA via Root-Mean-Square-Deviation-Driven Energy Minimization with Flexible Ligands and Flexible Targets

(2008) Christophe Guilbert et al.   Journal of Chemical Information and Modeling

Stochastic Gating and Drug–Ribosome Interactions

(2008) Andrea C. Vaiana et al.   JOURNAL OF MOLECULAR BIOLOGY