Bmp6 Expression Can Be Regulated Independently of Liver Iron in Mice

Ferritin upregulates hepatic expression of bone morphogenetic protein 6 and hepcidin in mice

(2012) Qi Feng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Decreased hepcidin expression in murine  -thalassemia is associated with suppression of Bmp/Smad signaling

(2012) N. L. Parrow et al.   BLOOD

Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression

(2012) David M. Frazer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice

(2012) Zhuzhen Zhang et al.   HEPATOLOGY

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

(2011) W. Chen et al.   BLOOD

Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses

(2011) Z. Zhang et al.   BLOOD

Hepcidin and iron regulation, 10 years later

(2011) T. Ganz   BLOOD

Hemojuvelin is essential for transferrin-dependent and transferrin-independent hepcidin expression in mice

(2011) T. B. Bartnikas et al.   HAEMATOLOGICA

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

(2011) Emilio Ramos et al.   HEPATOLOGY

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

(2011) Elena Corradini et al.   HEPATOLOGY

Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice

(2010) T. B. Bartnikas et al.   BLOOD

Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein

(2010) A.-S. Zhang et al.   BLOOD

Effect of erythropoietin on hepcidin expression in hemojuvelin-mutant mice

(2010) Jan Krijt et al.   BLOOD CELLS MOLECULES AND DISEASES

Transferrin therapy ameliorates disease in β-thalassemic mice

(2010) Huihui Li et al.   NATURE MEDICINE

Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes

(2009) G. Ramey et al.   HAEMATOLOGICA

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

(2009) Daniel F. Wallace et al.   HEPATOLOGY

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

(2009) Delphine Meynard et al.   NATURE GENETICS

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

(2009) Billy Andriopoulos Jr et al.   NATURE GENETICS

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

(2008) L. Kautz et al.   BLOOD

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBP 

(2008) J. P. Pinto et al.   BLOOD

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

(2008) Paul J. Schmidt et al.   Cell Metabolism