Bradykinin receptor antagonists – a review of the patent literature 2005 – 2008

Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists

(2008) Jian Jeffrey Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bradykinin B1 receptor antagonists: An α-hydroxy amide with an improved metabolism profile

(2008) Scott D. Kuduk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Aryl sulfones as novel Bradykinin B1 receptor antagonists for treatment of chronic pain

(2008) Kaustav Biswas et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1-Benzylbenzimidazoles: The discovery of a novel series of bradykinin B1 receptor antagonists

(2008) Qin Guo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The relevance of kinin B1receptor upregulation in a mouse model of colitis

(2008) D B Hara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Knee osteoarthritis: a role for bradykinin?

(2008) S. Meini et al.   INFLAMMATION RESEARCH

2-Aminobenzophenones as a Novel Class of Bradykinin B1Receptor Antagonists

(2008) Dai-Shi Su et al.   JOURNAL OF MEDICINAL CHEMISTRY

CYP2C75-Involved Autoinduction of Metabolism in Rhesus Monkeys of Methyl 3-Chloro-3'-fluoro-4'- carbonyl)amino]ethyl}-1,1'-biphenyl-2-carboxylate (MK-0686), a Bradykinin B1 Receptor Antagonist

(2008) C. Tang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Icatibant

(2008) Konrad Bork et al.   NATURE REVIEWS DRUG DISCOVERY

The non-peptide kinin receptor antagonists FR 173657 and SSR 240612: Preclinical evidence for the treatment of skin inflammation

(2008) Evelise Fernandes Pietrovski et al.   REGULATORY PEPTIDES

A new class of bradykinin B1 receptor antagonists with high oral bioavailability and minimal PXR activity

(2007) Dong-Mei Feng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

α-Hydroxy amides as a novel class of bradykinin B1 selective antagonists

(2007) Michael R. Wood et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS