Human A53T α-Synuclein Causes Reversible Deficits in Mitochondrial Function and Dynamics in Primary Mouse Cortical Neurons
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Human A53T α-Synuclein Causes Reversible Deficits in Mitochondrial Function and Dynamics in Primary Mouse Cortical Neurons
Authors
Keywords
-
Journal
PLoS One
Volume 8, Issue 12, Pages e85815
Publisher
Public Library of Science (PLoS)
Online
2014-01-01
DOI
10.1371/journal.pone.0085815
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A method to measure cardiac autophagic flux in vivo
- (2014) Eri Iwai-Kanai et al. Autophagy
- Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
- (2014) Daniel J. Klionsky et al. Autophagy
- Kinesin-1–syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport
- (2013) Yanmin Chen et al. JOURNAL OF CELL BIOLOGY
- Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson’s disease
- (2012) Weilin Xie et al. JOURNAL OF NEUROCHEMISTRY
- Autophagy modulation as a potential therapeutic target for diverse diseases
- (2012) David C. Rubinsztein et al. NATURE REVIEWS DRUG DISCOVERY
- Extracellular signal-regulated kinase is involved in alpha-synuclein-induced mitochondrial dynamic disorders by regulating dynamin-like protein 1
- (2012) Ya-Xing Gui et al. NEUROBIOLOGY OF AGING
- Early and Selective Impairments in Axonal Transport Kinetics of Synaptic Cargoes Induced by Soluble Amyloid β-Protein Oligomers
- (2012) Yong Tang et al. TRAFFIC
- Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database
- (2012) Christina M. Lill et al. PLoS Genetics
- The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity
- (2012) Erin K. Butler et al. PLoS Genetics
- Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria
- (2012) Song Liu et al. PLoS Genetics
- DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
- (2011) Melissa K. McCoy et al. Autophagy
- Assessing mitochondrial dysfunction in cells
- (2011) Martin D. Brand et al. BIOCHEMICAL JOURNAL
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy
- (2011) Vinay Choubey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trafficking Kinesin Protein (TRAK)-mediated Transport of Mitochondria in Axons of Hippocampal Neurons
- (2011) Kieran Brickley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein
- (2011) Ken Nakamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Parkinsonian Mimetic, MPP+, Specifically Impairs Mitochondrial Transport in Dopamine Axons
- (2011) J. S. Kim-Han et al. JOURNAL OF NEUROSCIENCE
- Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
- (2011) S. Lee et al. JOURNAL OF NEUROSCIENCE
- Pathological roles of α-synuclein in neurological disorders
- (2011) Kostas Vekrellis et al. LANCET NEUROLOGY
- Fighting neurodegeneration with rapamycin: mechanistic insights
- (2011) Jordi Bové et al. NATURE REVIEWS NEUROSCIENCE
- Mitochondria: The Next (Neurode)Generation
- (2011) Eric A. Schon et al. NEURON
- Mitochondrial matrix Ca2+ as an intrinsic signal regulating mitochondrial motility in axons
- (2011) K. T. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- α-Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson's disease
- (2010) Kalpita Banerjee et al. FEBS LETTERS
- Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
- (2010) C. Rose et al. HUMAN MOLECULAR GENETICS
- The Transgenic Overexpression of α-Synuclein and Not Its Related Pathology Associates with Complex I Inhibition
- (2010) Virginie Loeb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
- (2010) Ashley R. Winslow et al. JOURNAL OF CELL BIOLOGY
- Evidence That Myosin Activity Opposes Microtubule-Based Axonal Transport of Mitochondria
- (2010) D. Pathak et al. JOURNAL OF NEUROSCIENCE
- Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons
- (2010) T A Atkin et al. MOLECULAR PSYCHIATRY
- Autophagy gone awry in neurodegenerative diseases
- (2010) Esther Wong et al. NATURE NEUROSCIENCE
- Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
- (2010) H. Mortiboys et al. NEUROLOGY
- Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
- (2010) Shankar J. Chinta et al. NEUROSCIENCE LETTERS
- Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy
- (2010) Leslie Crews et al. PLoS One
- The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility
- (2009) Xinnan Wang et al. CELL
- The genetics of Parkinson's syndromes: a critical review
- (2009) John Hardy et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
- (2009) H. Chen et al. HUMAN MOLECULAR GENETICS
- Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
- (2009) Mordhwaj S. Parihar et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
- (2009) Ruben K. Dagda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein modulation of Ca2+signaling in human neuroblastoma (SH-SY5Y) cells
- (2009) Nishani T. Hettiarachchi et al. JOURNAL OF NEUROCHEMISTRY
- Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses
- (2009) Andrew F. MacAskill et al. NEURON
- Control of mitochondrial transport and localization in neurons
- (2009) Andrew F. MacAskill et al. TRENDS IN CELL BIOLOGY
- Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term Facilitation
- (2008) Jian-Sheng Kang et al. CELL
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking
- (2008) A. L. Orr et al. JOURNAL OF NEUROSCIENCE
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
- (2008) B. Boland et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells
- (2008) Shaik Shavali et al. NEUROSCIENCE LETTERS
- Mutant huntingtin and mitochondrial dysfunction
- (2008) Ella Bossy-Wetzel et al. TRENDS IN NEUROSCIENCES
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now