From Knock-Out Phenotype to Three-Dimensional Structure of a Promising Antibiotic Target from Streptococcus pneumoniae

Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition

(2013) Sarah C. Atkinson et al.   PLANT MOLECULAR BIOLOGY

Amino acid substitutions at glutamate-354 in dihydrolipoamide dehydrogenase of Escherichia coli lower the sensitivity of pyruvate dehydrogenase to NADH

(2012) Z. Sun et al.   MICROBIOLOGY-SGM

Tetrahydrodipicolinate N-Succinyltransferase and Dihydrodipicolinate Synthase from Pseudomonas aeruginosa: Structure Analysis and Gene Deletion

(2012) Robert Schnell et al.   PLoS One

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine

(2012) Sarah C. Atkinson et al.   PLoS One

Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana

(2012) Michael D. W. Griffin et al.   PLoS One

Structural and Dynamic Requirements for Optimal Activity of the Essential Bacterial Enzyme Dihydrodipicolinate Synthase

(2012) C. F. Reboul et al.   PLoS Computational Biology

Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa

(2011) Navpreet Kaur et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

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(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal structure of dihydrodipicolinate synthase from Hahella chejuensis at 1.5Å resolution

(2010) Beom Sik Kang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Crystallization of dihydrodipicolinate synthase from a clinical isolate ofStreptococcus pneumoniae

(2009) Natalia E. Sibarani et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Structure of dihydrodipicolinate synthase fromMethanocaldococcus jannaschii

(2009) Balasundaram Padmanabhan et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Exploring the dihydrodipicolinate synthase tetramer: How resilient is the dimer–dimer interface?

(2009) Michael D.W. Griffin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis

(2009) L.J. Domigan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis

(2009) Sean R.A. Devenish et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax

(2009) Jarrod E. Voss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of ldh expression during biotin-limited growth of Corynebacterium glutamicum

(2009) C. Dietrich et al.   MICROBIOLOGY-SGM

Characterization and crystal structure of lysine insensitive Corynebacterium glutamicum dihydrodipicolinate synthase (cDHDPS) protein

(2008) Elena A. Rice et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Crystal structure and kinetic study of dihydrodipicolinate synthase fromMycobacterium tuberculosis

(2008) Georgia Kefala et al.   BIOCHEMICAL JOURNAL

Structural and functional characterization ofStaphylococcus aureusdihydrodipicolinate synthase

(2008) Tavarekere S. Girish et al.   FEBS LETTERS

Structure and Evolution of a Novel Dimeric Enzyme from a Clinically Important Bacterial Pathogen

(2008) Benjamin R. Burgess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of Quaternary Structure in a Homotetrameric Enzyme

(2008) Michael D.W. Griffin et al.   JOURNAL OF MOLECULAR BIOLOGY