Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition

Effect of phyllotactic position and cultural treatments toward successful direct shoot organogenesis in dwarf ‘Pixie’ grapevine (Vitis vinifera L.)

(2012) Kathie L. Nicholson et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine

(2012) Sarah C. Atkinson et al.   PLoS One

Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana

(2012) Michael D. W. Griffin et al.   PLoS One

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevineVitis vinifera

(2011) Sarah C. Atkinson et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

How essential is the ‘essential’ active-site lysine in dihydrodipicolinate synthase?

(2010) Tatiana P. Soares da Costa et al.   BIOCHIMIE

Exploring the dihydrodipicolinate synthase tetramer: How resilient is the dimer–dimer interface?

(2009) Michael D.W. Griffin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis

(2009) L.J. Domigan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis

(2009) Sean R.A. Devenish et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

New insights into the mechanism of dihydrodipicolinate synthase using isothermal titration calorimetry

(2009) Andrew C. Muscroft-Taylor et al.   BIOCHIMIE

Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax

(2009) Jarrod E. Voss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The high-resolution structure of dihydrodipicolinate synthase fromEscherichia colibound to its first substrate, pyruvate

(2008) Sean R. A. Devenish et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Crystal structure and kinetic study of dihydrodipicolinate synthase fromMycobacterium tuberculosis

(2008) Georgia Kefala et al.   BIOCHEMICAL JOURNAL

Isothermal Titration Microcalorimetry Reveals the Cooperative and Noncompetitive Nature of Inhibition ofSinorhizobium melilotiL5-30 Dihydrodipicolinate Synthase by (S)-Lysine†

(2008) Christopher P. Phenix et al.   BIOCHEMISTRY

Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues

(2008) Berin A. Boughton et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural and functional characterization ofStaphylococcus aureusdihydrodipicolinate synthase

(2008) Tavarekere S. Girish et al.   FEBS LETTERS

Structure and Evolution of a Novel Dimeric Enzyme from a Clinically Important Bacterial Pathogen

(2008) Benjamin R. Burgess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of Quaternary Structure in a Homotetrameric Enzyme

(2008) Michael D.W. Griffin et al.   JOURNAL OF MOLECULAR BIOLOGY

Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase

(2008) Renwick C.J. Dobson et al.   PROTEIN SCIENCE

Inhibiting dihydrodipicolinate synthase across species: Towards specificity for pathogens?

(2007) Voula Mitsakos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS