Altered Cardiac Electrophysiology and SUDEP in a Model of Dravet Syndrome

Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias

(2013) Anthony W. Herren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism

(2013) Yu Liu et al.   ANNALS OF NEUROLOGY

Super-resolution fluorescence microscopy of the cardiac connexome reveals plakophilin-2 inside the connexin43 plaque

(2013) Esperanza Agullo-Pascual et al.   CARDIOVASCULAR RESEARCH

Sudden unexpected death in a mouse model of Dravet syndrome

(2013) Franck Kalume et al.   JOURNAL OF CLINICAL INVESTIGATION

Distribution and function of sodium channel subtypes in human atrial myocardium

(2013) Susann G. Kaufmann et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Channelopathies from mutations in the cardiac sodium channel protein complex

(2013) Graham S. Adsit et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

QT and P wave dispersion and heart rate variability in patients with Dravet syndrome

(2012) Yakup Ergul et al.   ACTA NEUROLOGICA BELGICA

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

(2012) Cecile Terrenoire et al.   JOURNAL OF GENERAL PHYSIOLOGY

The Sodium Channel Accessory Subunit Nav 1 Regulates Neuronal Excitability through Modulation of Repolarizing Voltage-Gated K+ Channels

(2012) C. Marionneau et al.   JOURNAL OF NEUROSCIENCE

The β1-Subunit of Nav1.5 Cardiac Sodium Channel Is Required for a Dominant Negative Effect through α-α Interaction

(2012) Aurélie Mercier et al.   PLoS One

Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia

(2012) M. L. Milstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

(2012) C. S. Cheah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiomyocytes Obtained From Induced Pluripotent Stem Cells With Long-QT Syndrome 3 Recapitulate Typical Disease-Specific Features In Vitro

(2011) Daniela Malan et al.   CIRCULATION RESEARCH

Insights into pathophysiology and therapy from a mouse model of Dravet syndrome

(2011) John C. Oakley et al.   EPILEPSIA

Severe myoclonic epilepsy in infancy (Dravet syndrome) 30 years later

(2011) Charlotte Dravet et al.   EPILEPSIA

Electrical and autonomic cardiac function in patients with Dravet syndrome

(2011) Angelica B. Delogu et al.   EPILEPSIA

A null mutation of the neuronal sodium channel NaV1.6 disrupts action potential propagation and excitation-contraction coupling in the mouse heart

(2011) Sami F. Noujaim et al.   FASEB JOURNAL

Sudden unexpected death in epilepsy

(2011) Simon Shorvon et al.   LANCET

Sudden Unexpected Death in Epilepsy

(2010) Maromi Nei et al.   Current Neurology and Neuroscience Reports

Sodium channel SCN1A and epilepsy: Mutations and mechanisms

(2010) Andrew Escayg et al.   EPILEPSIA

Too long or too short? New insights into abnormal cardiac repolarization in people with chronic epilepsy and its potential role in sudden unexpected death

(2010) Rainer Surges et al.   EPILEPSIA

Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6

(2010) Georgina Estrada et al.   PEPTIDES

Biophysical characterisation of the persistent sodium current of the Nav1.6 neuronal sodium channel: a single-channel analysis

(2010) Aurélien Chatelier et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Pathologic cardiac repolarization in pharmacoresistant epilepsy and its potential role in sudden unexpected death in epilepsy: A case-control study

(2009) Rainer Surges et al.   EPILEPSIA

Lengthening of corrected QT during epileptic seizures

(2009) Ruth Brotherstone et al.   EPILEPSIA

SUDDEN UNEXPECTED NEAR DEATH IN EPILEPSY: MALIGNANT ARRHYTHMIA FROM A PARTIAL SEIZURE

(2009) P. S. Espinosa et al.   NEUROLOGY

Voltage-gated Navchannel targeting in the heart requires an ankyrin-G–dependent cellular pathway

(2008) John S. Lowe et al.   JOURNAL OF CELL BIOLOGY

Voltage-Gated Na+ Channel  1 Subunit-Mediated Neurite Outgrowth Requires Fyn Kinase and Contributes to Postnatal CNS Development In Vivo

(2008) W. J. Brackenbury et al.   JOURNAL OF NEUROSCIENCE

New SCN5A mutation in a SUDEP victim with idiopathic epilepsy

(2008) Dag Aurlien et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY