Activation of Rac-1 and RhoA Contributes to Podocyte Injury in Chronic Kidney Disease

Benefits and Harms of Statin Therapy for Persons With Chronic Kidney Disease

(2013) Suetonia C. Palmer et al.   ANNALS OF INTERNAL MEDICINE

Rho-Kinase Inhibitor, Fasudil, Prevents Neuronal Apoptosis via the Akt Activation and PTEN Inactivation in the Ischemic Penumbra of Rat Brain

(2012) Jianhua Wu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Rac1/PAK1 signaling promotes epithelial-mesenchymal transition of podocytes in vitro via triggering β-catenin transcriptional activity under high glucose conditions

(2012) Zhimei Lv et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Angiotensin II- and Salt-Induced Kidney Injury through Rac1-Mediated Mineralocorticoid Receptor Activation

(2012) W. Kawarazaki et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice

(2011) Hong-yi Yao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanisms and consequences of TGF-ß overexpression by podocytes in progressive podocyte disease

(2011) Hyun Soon Lee   CELL AND TISSUE RESEARCH

Non-Smad signaling pathways

(2011) Yabing Mu et al.   CELL AND TISSUE RESEARCH

Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor–dependent pathway

(2011) Shigeru Shibata et al.   JOURNAL OF CLINICAL INVESTIGATION

Treatment of chronic kidney disease

(2011) Jeffrey M. Turner et al.   KIDNEY INTERNATIONAL

Chronic kidney disease

(2011) Andrew S Levey et al.   LANCET

Selective Rac1 inhibition protects renal tubular epithelial cells from oxalate-induced NADPH oxidase-mediated oxidative cell injury

(2011) Vijayalakshmi Thamilselvan et al.   UROLOGICAL RESEARCH

Rho kinase inhibition in diabetic nephropathy

(2010) Radko Komers   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Novel aspects of the roles of Rac1 GTPase in the cardiovascular system

(2010) Naoki Sawada et al.   CURRENT OPINION IN PHARMACOLOGY

Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure

(2010) Radko Komers et al.   KIDNEY INTERNATIONAL

Inhibition of the Soluble Epoxide Hydrolase Promotes Albuminuria in Mice with Progressive Renal Disease

(2010) Oliver Jung et al.   PLoS One

Role of Rac1 GTPase in JNK signaling and delayed neuronal cell death following global cerebral ischemia

(2009) Quan-Guang Zhang et al.   BRAIN RESEARCH

Erbin and the NF2 Tumor Suppressor Merlin Cooperatively Regulate Cell-Type-Specific Activation of PAK2 by TGF-β

(2009) Mark C. Wilkes et al.   DEVELOPMENTAL CELL

Pharmacological Characterization of SAR407899, a Novel Rho-Kinase Inhibitor

(2009) Matthias Löhn et al.   HYPERTENSION

Mechanical forces and TGF 1 reduce podocyte adhesion through  3 1 integrin downregulation

(2009) C. Dessapt et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Applications for ROCK kinase inhibition

(2008) Michael F Olson   CURRENT OPINION IN CELL BIOLOGY

RhoA/Rho-Kinase Contribute to the Pathogenesis of Diabetic Renal Disease

(2008) F. Peng et al.   DIABETES

Inhibition of Rac1 decreases the severity of pancreatitis and pancreatitis-associated lung injury in mice

(2008) Marcelo G. Binker et al.   EXPERIMENTAL PHYSIOLOGY

Mechanisms of angiotensin II signaling on cytoskeleton of podocytes

(2008) Hsiang-Hao Hsu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease

(2008) Shigeru Shibata et al.   NATURE MEDICINE