An Internal Ribosome Entry Site (IRES) Mutant Library for Tuning Expression Level of Multiple Genes in Mammalian Cells

Control of IgG LC:HC ratio in stably transfected CHO cells and study of the impact on expression, aggregation, glycosylation and conformational stability

(2013) Steven C.L. Ho et al.   JOURNAL OF BIOTECHNOLOGY

Comparison of Internal Ribosome Entry Site (IRES) and Furin-2A (F2A) for Monoclonal Antibody Expression Level and Quality in CHO Cells

(2013) Steven C. L. Ho et al.   PLoS One

Light it up: Highly efficient multigene delivery in mammalian cells

(2011) Simon Trowitzsch et al.   BIOESSAYS

Impact of gene vector design on the control of recombinant monoclonal antibody production by chinese hamster ovary cells

(2011) Sarah L. Davies et al.   BIOTECHNOLOGY PROGRESS

IRES-mediated Tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines

(2011) Steven C.L. Ho et al.   JOURNAL OF BIOTECHNOLOGY

MultiBac: expanding the research toolbox for multiprotein complexes

(2011) Christoph Bieniossek et al.   TRENDS IN BIOCHEMICAL SCIENCES

Inhibition of 2A-mediated ‘cleavage’ of certain artificial polyproteins bearing N-terminal signal sequences

(2009) Pablo de Felipe et al.   Biotechnology Journal

Mutated polyadenylation signals for controlling expression levels of multiple genes in mammalian cells

(2008) Yuansheng Yang et al.   BIOTECHNOLOGY AND BIOENGINEERING

A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?

(2008) Janet Chusainow et al.   BIOTECHNOLOGY AND BIOENGINEERING

A clone screening method using mRNA levels to determine specific productivity and product quality for monoclonal antibodies

(2008) Christina J. Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

Multi-gene gateway clone design for expression of multiple heterologous genes in living cells: Eukaryotic clones containing two and three ORF multi-gene cassettes expressed from a single promoter

(2008) Yukari Sasaki et al.   JOURNAL OF BIOTECHNOLOGY

On the Optimal Ratio of Heavy to Light Chain Genes for Efficient Recombinant Antibody Production by CHO Cells

(2005) Stefan Schlatter et al.   BIOTECHNOLOGY PROGRESS