Inhibition of 2A-mediated ‘cleavage’ of certain artificial polyproteins bearing N-terminal signal sequences

CD4+CD25- T Cells Transduced to Express MHC Class I-Restricted Epitope-Specific TCR Synthesize Th1 Cytokines and Exhibit MHC Class I-Restricted Cytolytic Effector Function in a Human Melanoma Model

(2014) A. Chhabra et al.   JOURNAL OF IMMUNOLOGY

Redirecting Therapeutic T Cells against Myelin-Specific T Lymphocytes Using a Humanized Myelin Basic Protein-HLA-DR2-  Chimeric Receptor

(2014) I. Moisini et al.   JOURNAL OF IMMUNOLOGY

Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame

(2009) Lijian Shao et al.   CELL RESEARCH

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

(2009) Keisuke Kaji et al.   NATURE

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

Retroviral transfer of a dominant TCR prevents surface expression of a large proportion of the endogenous TCR repertoire in human T cells

(2008) D P Hart et al.   GENE THERAPY

Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition

(2008) S Yang et al.   GENE THERAPY

Differentiation of human embryonic stem cells into osteogenic or hematopoietic lineages: A dose-dependent effect of osterix over-expression

(2008) Elerin Kärner et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Occurrence, function and evolutionary origins of '2A-like' sequences in virus genomes

(2008) G. A. Luke et al.   JOURNAL OF GENERAL VIROLOGY

Site-Specific Release of Nascent Chains from Ribosomes at a Sense Codon

(2008) V. A. Doronina et al.   MOLECULAR AND CELLULAR BIOLOGY

Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity

(2008) Jeff Holst et al.   NATURE IMMUNOLOGY

Reprogramming of murine and human somatic cells using a single polycistronic vector

(2008) B. W. Carey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

(2008) K. Okita et al.   SCIENCE

Lentiviral-Mediated HoxB4 Expression in Human Embryonic Stem Cells Initiates Early Hematopoiesis in a Dose-Dependent Manner but Does Not Promote Myeloid Differentiation

(2008) Christian Unger et al.   STEM CELLS

Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

(2008) Cesar A. Sommer et al.   STEM CELLS