Solution NMR Structure and Histone Binding of the PHD Domain of Human MLL5

ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function

(2013) Gershon Celniker et al.   ISRAEL JOURNAL OF CHEMISTRY

Mixed Lineage Leukemia 5 (MLL5) Protein Regulates Cell Cycle Progression and E2F1-responsive Gene Expression via Association with Host Cell Factor-1 (HCF-1)

(2013) Peipei Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis for chromatin binding and regulation of MLL5

(2013) M. Ali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MLL5 maintains genomic integrity by regulating the stability of the chromosomal passenger complex through a functional interaction with Borealin

(2012) J. Liu et al.   JOURNAL OF CELL SCIENCE

Structure and Mechanisms of Lysine Methylation Recognition by the Chromodomain in Gene Transcription

(2011) Kyoko L. Yap et al.   BIOCHEMISTRY

PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression

(2011) Eerappa Rajakumara et al.   MOLECULAR CELL

Camptothecin-induced downregulation of MLL5 contributes to the activation of tumor suppressor p53

(2011) F Cheng et al.   ONCOGENE

Structural and Histone Binding Ability Characterizations of Human PWWP Domains

(2011) Hong Wu et al.   PLoS One

Mll5 Is Required for Normal Spermatogenesis

(2011) Damian B. Yap et al.   PLoS One

Structure and function of WD40 domain proteins

(2011) Chao Xu et al.   Protein & Cell

Phosphorylation of Mixed Lineage Leukemia 5 by Cdc2 Affects Its Cellular Distribution and Is Required for Mitotic Entry

(2010) Jie Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel strategy for NMR resonance assignment and protein structure determination

(2010) Alexander Lemak et al.   JOURNAL OF BIOMOLECULAR NMR

PHD Fingers: Epigenetic Effectors and Potential Drug Targets

(2010) C. A. Musselman et al.   MOLECULAR INTERVENTIONS

Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b

(2010) Lei Zeng et al.   NATURE

GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis

(2009) Ryoji Fujiki et al.   NATURE

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

(2009) Francesca Chignola et al.   NUCLEIC ACIDS RESEARCH

MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation

(2009) S. Sebastian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MBT domain proteins in development and disease

(2009) Roberto Bonasio et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator

(2009) Suvobrata Chakravarty et al.   STRUCTURE

Mll5 contributes to hematopoietic stem cell fitness and homeostasis

(2008) Y. Zhang et al.   BLOOD

Loss of Mll5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation

(2008) M. Heuser et al.   BLOOD

Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog Mll5

(2008) V. Madan et al.   BLOOD

Sequence specific resonance assignment via Multicanonical Monte Carlo search using an ABACUS approach

(2008) Alexander Lemak et al.   JOURNAL OF BIOMOLECULAR NMR

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

(2008) Robert E Collins et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A SPOT on the chromatin landscape? Histone peptide arrays as a tool for epigenetic research

(2008) Nataliya Nady et al.   TRENDS IN BIOCHEMICAL SCIENCES