Blocking Plasmodium falciparum Development via Dual Inhibition of Hemoglobin Degradation and the Ubiquitin Proteasome System by MG132

Proteasome Inhibitors: An Expanding Army Attacking a Unique Target

(2012) Alexei F. Kisselev et al.   CHEMISTRY & BIOLOGY

Synthesis and Insight into the Structure–Activity Relationships of Chalcones as Antimalarial Agents

(2012) Narender Tadigoppula et al.   JOURNAL OF MEDICINAL CHEMISTRY

Expression, Characterization, and Cellular Localization of Knowpains, Papain-Like Cysteine Proteases of the Plasmodium knowlesi Malaria Parasite

(2012) Rajesh Prasad et al.   PLoS One

The Ionic and Hydrophobic Interactions Are Required for the Auto Activation of Cysteine Proteases of Plasmodium falciparum

(2012) Srinivasan Sundararaj et al.   PLoS One

Unraveling the Ubiquitome of the Human Malaria Parasite

(2011) Nadia Ponts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distribution and Biochemical Properties of an M1-family Aminopeptidase inPlasmodium falciparumIndicate a Role in Vacuolar Hemoglobin Catabolism

(2011) Daniel Ragheb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MG132 as a proteasome inhibitor induces cell growth inhibition and cell death in A549 lung cancer cells via influencing reactive oxygen species and GSH level

(2010) Yong Hwan Han et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Falcipain Inhibitors: Optimization Studies of the 2-Pyrimidinecarbonitrile Lead Series†

(2010) Jose M. Coterón et al.   JOURNAL OF MEDICINAL CHEMISTRY

Biochemical Properties of a Novel Cysteine Protease of Plasmodium vivax, Vivapain-4

(2010) Byoung-Kuk Na et al.   PLoS Neglected Tropical Diseases

The Proteasome Inhibitor Epoxomicin Has Potent Plasmodium falciparum Gametocytocidal Activity

(2009) B. Czesny et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The pharmacological NFκB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation

(2009) Alfeu Zanotto-Filho et al.   CANCER LETTERS

Hemoglobin Cleavage Site-Specificity of the Plasmodium falciparum Cysteine Proteases Falcipain-2 and Falcipain-3

(2009) Shoba Subramanian et al.   PLoS One

Improved prediction of malaria degradomes by supervised learning with SVM and profile kernel

(2008) Rui Kuang et al.   GENETICA

Inhibition of rat liver cathepsins B and L by the peptide aldehyde benzyloxycarbonyl-leucyl-leucyl-leucinal and its analogues

(2008) Hisashi Ito et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon

(2008) Andrea Kreidenweiss et al.   MALARIA JOURNAL