Neuropathic Pain in Rats with a Partial Sciatic Nerve Ligation Is Alleviated by Intravenous Injection of Monoclonal Antibody to High Mobility Group Box-1

Importance of glial activation in neuropathic pain

(2013) Joanna Mika et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microglial Regulation of Neuropathic Pain

(2013) Makoto Tsuda et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Anti-high mobility group box-1 antibody therapy for traumatic brain injury

(2012) Yu Okuma et al.   ANNALS OF NEUROLOGY

High-mobility group box 1 contributes to mechanical allodynia and spinal astrocytic activation in a mouse model of type 2 diabetes

(2012) Peng-Cheng Ren et al.   BRAIN RESEARCH BULLETIN

The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain

(2012) Polina Feldman et al.   Journal of Neuroinflammation

Glia as a Link between Neuroinflammation and Neuropathic Pain

(2012) Mithilesh Kumar Jha et al.   Immune Network

JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats

(2011) Makoto Tsuda et al.   BRAIN

Signaling pathways of ATP-induced PGE2 release in spinal cord astrocytes are EGFR transactivation-dependent

(2011) Maosheng Xia et al.   GLIA

Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes and microglia

(2011) Wenwen Sheng et al.   Journal of Neuroinflammation

Peripheral Nerve Injury Alters Blood-Spinal Cord Barrier Functional and Molecular Integrity through a Selective Inflammatory Pathway

(2011) S. Echeverry et al.   JOURNAL OF NEUROSCIENCE

Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood–Brain Barrier From Ischemia-Induced Disruption in Rats

(2011) Jiyong Zhang et al.   STROKE

High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Peter Kanellakis et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Spinal high-mobility group box 1 contributes to mechanical allodynia in a rat model of bone cancer pain

(2010) Wei Tong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Spinal Astrocytes as Therapeutic Targets for Pathological Pain

(2010) Takayuki Nakagawa et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Peripheral Nerve Injury and TRPV1-Expressing Primary Afferent C-Fibers Cause Opening of the Blood-Brain Barrier

(2010) Simon Beggs et al.   Molecular Pain

Induction of high mobility group box-1 in dorsal root ganglion contributes to pain hypersensitivity after peripheral nerve injury

(2010) Masayuki Shibasaki et al.   PAIN

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P2X4-Receptor-Mediated Synthesis and Release of Brain-Derived Neurotrophic Factor in Microglia Is Dependent on Calcium and p38-Mitogen-Activated Protein Kinase Activation

(2009) T. Trang et al.   JOURNAL OF NEUROSCIENCE

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(2008) John Klune et al.   MOLECULAR MEDICINE