DNA Topoisomerases Participate in Fragility of the Oncogene RET

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RET, ROS1 and ALK fusions in lung cancer

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Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes

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Molecular genetics and diagnosis of thyroid cancer

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All tangled up: how cells direct, manage and exploit topoisomerase function

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DNA Instability at Chromosomal Fragile Sites in Cancer

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Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites

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Signatures of mutation and selection in the cancer genome

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Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats

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DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells

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Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites

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Rising Thyroid Cancer Incidence in the United States by Demographic and Tumor Characteristics, 1980-2005

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Rational Design and Semisynthesis of Betulinic Acid Analogues as Potent Topoisomerase Inhibitors

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Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

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DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D

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R loops stimulate genetic instability of CTG{middle dot}CAG repeats

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Childhood papillary thyroid cancer as second malignancy after successful treatment of rhabdomyosarcoma

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Replication timing of two human common fragile sites: FRA1H and FRA2G

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Secondary Thyroid Papillary Carcinoma in Osteosarcoma Patients: Report of Two Cases

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Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase II 

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Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis

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