Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

(2012) E. Ramos et al.   BLOOD

Dihydroartemisinin Exerts Its Anticancer Activity through Depleting Cellular Iron via Transferrin Receptor-1

(2012) Qian Ba et al.   PLoS One

Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation

(2011) Chia Chi Sun et al.   AMERICAN JOURNAL OF HEMATOLOGY

Influence of DMT1 and iron status on inflammatory responses in the lung

(2011) Jonghan Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pharmacology of Iron Transport

(2011) Shaina L. Byrne et al.   Annual Review of Pharmacology and Toxicology

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

(2011) I. Theurl et al.   BLOOD

Intestinal DMT1 Cotransporter Is Down-regulated by Hepcidin via Proteasome Internalization and Degradation

(2011) Carole Brasse–Lagnel et al.   GASTROENTEROLOGY

Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload

(2011) Gloria C. Preza et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Importance of the Stem Cell Marker Prominin-1/CD133 in the Uptake of Transferrin and in Iron Metabolism in Human Colon Cancer Caco-2 Cells

(2011) Erika Bourseau-Guilmain et al.   PLoS One

Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin

(2010) P. J. Schmidt et al.   BLOOD

Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice

(2010) J. Gao et al.   BLOOD

Down-regulation of hepcidin resulting from long-term treatment with an anti-IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman disease

(2010) S.-N. J. Song et al.   BLOOD

Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages

(2010) A. Auriac et al.   HAEMATOLOGICA

ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin

(2010) Ningning Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural and synthetic STAT3 inhibitors reduce hepcidin expression in differentiated mouse hepatocytes expressing the active phosphorylated STAT3 form

(2010) Nadia Fatih et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The role of transferrin receptor 1 and 2 in transferrin-bound iron uptake in human hepatoma cells

(2009) Carly E. Herbison et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Small molecule inhibitors of divalent metal transporter-1

(2009) Peter D. Buckett et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression

(2009) Junwei Gao et al.   Cell Metabolism

Antitumor activity and mechanism of action of the iron chelator, Dp44mT, against leukemic cells

(2008) Egarit Noulsri et al.   AMERICAN JOURNAL OF HEMATOLOGY

Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism

(2008) T. Lambe et al.   BLOOD

Hfe Acts in Hepatocytes to Prevent Hemochromatosis

(2008) Maja Vujić Spasić et al.   Cell Metabolism

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

(2008) Paul J. Schmidt et al.   Cell Metabolism

The Small-Molecule Iron Transport Inhibitor Ferristatin/NSC306711 Promotes Degradation of the Transferrin Receptor

(2008) Lior Horonchik et al.   CHEMISTRY & BIOLOGY

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

(2008) Xian-Ping Dong et al.   NATURE

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE