Human APOBEC3A Isoforms Translocate to the Nucleus and Induce DNA Double Strand Breaks Leading to Cell Stress and Death

APOBEC3B is an enzymatic source of mutation in breast cancer

(2013) Michael B. Burns et al.   NATURE

Efficient Deamination of 5-Methylcytidine and 5-Substituted Cytidine Residues in DNA by Human APOBEC3A Cytidine Deaminase

(2013) Rodolphe Suspène et al.   PLoS One

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

(2013) Benjamin JM Taylor et al.   eLife

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma

(2012) T. Zhang et al.   HUMAN MOLECULAR GENETICS

Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3A

(2012) Michael A. Carpenter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Tribbles 3 Protects Nuclear DNA from Cytidine Deamination by APOBEC3A

(2012) Marie-Ming Aynaud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical Analysis of Hypermutation by the Deoxycytidine Deaminase APOBEC3A

(2012) Robin P. Love et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APOBEC3A, APOBEC3B, and APOBEC3H Haplotype 2 Restrict Human T-Lymphotropic Virus Type 1

(2012) M. Ooms et al.   JOURNAL OF VIROLOGY

Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G

(2012) Priyanga Wijesinghe et al.   NUCLEIC ACIDS RESEARCH

Evolution of the Primate APOBEC3A Cytidine Deaminase Gene and Identification of Related Coding Regions

(2012) Michel Henry et al.   PLoS One

Studies on the Restriction of Murine Leukemia Viruses by Mouse APOBEC3

(2012) Silvia Sanchez-Martinez et al.   PLoS One

Role of retroviral restriction factors in the interferon- -mediated suppression of HIV-1 in vivo

(2012) S. K. Pillai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells

(2012) Masanobu Shinohara et al.   Scientific Reports

Dissecting T Cell Contraction In Vivo Using a Genetically Encoded Reporter of Apoptosis

(2012) Kym R. Garrod et al.   Cell Reports

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Where did they come from? The origin of endogenous γ-H2AX foci in tumor cells

(2011) Asako J. Nakamura et al.   CELL CYCLE

APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

(2011) Sébastien Landry et al.   EMBO REPORTS

Genetic Editing of Herpes Simplex Virus 1 and Epstein-Barr Herpesvirus Genomes by Human APOBEC3 Cytidine Deaminases in Culture and In Vivo

(2011) R. Suspene et al.   JOURNAL OF VIROLOGY

Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism

(2011) R. Suspene et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOBEC3A Is a Specific Inhibitor of the Early Phases of HIV-1 Infection in Myeloid Cells

(2011) Gregory Berger et al.   PLoS Pathogens

DNA binding, cytotoxicity, and apoptotic-inducing activity of ruthenium(II) polypyridyl complex

(2010) P. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Innate Immune Signaling Induces High Levels of TC-specific Deaminase Activity in Primary Monocyte-derived Cells through Expression of APOBEC3A Isoforms

(2010) Beth K. Thielen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

(2010) Mark D Stenglein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

(2010) Eric W. Refsland et al.   NUCLEIC ACIDS RESEARCH

Massive APOBEC3 Editing of Hepatitis B Viral DNA in Cirrhosis

(2010) Jean-Pierre Vartanian et al.   PLoS Pathogens

Delayed kinetics of DNA double-strand break processing in normal and pathological aging

(2009) Olga A. Sedelnikova et al.   AGING CELL

Human Immunodeficiency Virus, Restriction Factors, and Interferon

(2009) Stuart Neil et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Induction of APOBEC3 In Vivo Causes Increased Restriction of Retrovirus Infection

(2009) C. M. Okeoma et al.   JOURNAL OF VIROLOGY

Defining APOBEC3 Expression Patterns in Human Tissues and Hematopoietic Cell Subsets

(2009) F. A. Koning et al.   JOURNAL OF VIROLOGY

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

A coming-of-age story: activation-induced cytidine deaminase turns 10

(2009) Rebecca K Delker et al.   NATURE IMMUNOLOGY

Genetic Editing of HBV DNA by Monodomain Human APOBEC3 Cytidine Deaminases and the Recombinant Nature of APOBEC3G

(2009) Michel Henry et al.   PLoS One

Balancing AID and DNA repair during somatic hypermutation

(2009) Man Liu et al.   TRENDS IN IMMUNOLOGY

The APOBEC3 Cytidine Deaminases: An Innate Defensive Network Opposing Exogenous Retroviruses and Endogenous Retroelements

(2008) Ya-Lin Chiu et al.   Annual Review of Immunology

AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations

(2008) Davide F. Robbiani et al.   CELL

Endogenous DNA damage clusters in human hematopoietic stem and progenitor cells

(2008) P BENNETT et al.   FREE RADICAL BIOLOGY AND MEDICINE

APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells

(2008) F.-x. Wang et al.   JOURNAL OF GENERAL VIROLOGY

APOBEC3-Independent Interferon-Induced Viral Clearance in Hepatitis B Virus Transgenic Mice

(2008) P. Turelli et al.   JOURNAL OF VIROLOGY

DNA strand breaks, neurodegeneration and aging in the brain

(2008) Sachin Katyal et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Two levels of protection for the B cell genome during somatic hypermutation

(2008) Man Liu et al.   NATURE

Powerful mutators lurking in the genome

(2008) V. Petit et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Evidence for Editing of Human Papillomavirus DNA by APOBEC3 in Benign and Precancerous Lesions

(2008) J.-P. Vartanian et al.   SCIENCE

Age to survive: DNA damage and aging

(2008) Björn Schumacher et al.   TRENDS IN GENETICS

Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence

(2008) Asako J Nakamura et al.   Epigenetics & Chromatin