Adding Diverse Noncanonical Backbones to Rosetta: Enabling Peptidomimetic Design

Androgen Receptor Antagonism by Divalent Ethisterone Conjugates in Castrate-Resistant Prostate Cancer Cells

(2012) Paul M. Levine et al.   ACS Chemical Biology

Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1

(2012) Pravas Kumar Baral et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Peptoids: Bio-Inspired Polymers as Potential Pharmaceuticals

(2012) Michelle T. Dohm et al.   CURRENT PHARMACEUTICAL DESIGN

Ordering of the N-Terminus of Human MDM2 by Small Molecule Inhibitors

(2012) Klaus Michelsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring Key Orientations at Protein–Protein Interfaces with Small Molecule Probes

(2012) Eunhwa Ko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design

(2012) P. Douglas Renfrew et al.   PLoS One

Remodeling a β-peptide bundle

(2012) Matthew A. Molski et al.   Chemical Science

Helix-mediated protein–protein interactions as targets for intervention using foldamers

(2011) Thomas A. Edwards et al.   AMINO ACIDS

Assessing Helical Protein Interfaces for Inhibitor Design

(2011) Brooke N. Bullock et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Computational Design of a β-Peptide That Targets Transmembrane Helices

(2011) Scott J. Shandler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain

(2011) Melissa D. Boersma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Extraordinarily Robust Polyproline Type I Peptoid Helices Generatedviathe Incorporation of α-Chiral AromaticN-1-Naphthylethyl Side Chains

(2011) Joseph R. Stringer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An orthosteric inhibitor of the Ras-Sos interaction

(2011) Anupam Patgiri et al.   Nature Chemical Biology

Human Sperm Binding Is Mediated by the Sialyl-Lewisx Oligosaccharide on the Zona Pellucida

(2011) P.-C. Pang et al.   SCIENCE

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

(2011) Helen Tran et al.   Jove-Journal of Visualized Experiments

Systematic Analysis of Helical Protein Interfaces Reveals Targets for Synthetic Inhibitors

(2010) Andrea L. Jochim et al.   ACS Chemical Biology

High Specificity in Protein Recognition by Hydrogen-Bond-Surrogate α-Helices: Selective Inhibition of the p53/MDM2 Complex

(2010) Laura K. Henchey et al.   CHEMBIOCHEM

Disrupting protein–protein interactions with non-peptidic, small molecule α-helix mimetics

(2010) Christopher G Cummings et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Development of a Rotamer Library for Use in β-Peptide Foldamer Computational Design

(2010) Scott J. Shandler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solid-Phase Synthesis of N-Substituted Glycine Oligomers (α‑Peptoids) and Derivatives

(2010) Adrian S. Culf et al.   MOLECULES

The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

(2010) Michelle L Stewart et al.   Nature Chemical Biology

Oligooxopiperazines as Nonpeptidic α-Helix Mimetics

(2010) Petra Tošovská et al.   ORGANIC LETTERS

Computational Design of a Self-Assembling β-Peptide Oligomer

(2010) Ivan V. Korendovych et al.   ORGANIC LETTERS

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

A Preliminary Survey of the Peptoid Folding Landscape

(2009) Glenn L. Butterfoss et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of Hypoxia Inducible Factor 1—Transcription Coactivator Interaction by a Hydrogen Bond Surrogate α-Helix

(2009) Laura K. Henchey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure–function relationships in peptoids: Recent advances toward deciphering the structural requirements for biological function

(2009) Sarah A. Fowler et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural and biological mimicry of protein surface recognition by  / -peptide foldamers

(2009) W. S. Horne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Peptidic Peptidomimetics

(2008) Dieter Seebach et al.   ACCOUNTS OF CHEMICAL RESEARCH

Foldamers with Heterogeneous Backbones

(2008) W. Seth Horne et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Hydrogen Bond Surrogate Approach for Stabilization of Short Peptide Sequences in α-Helical Conformation

(2008) Anupam Patgiri et al.   ACCOUNTS OF CHEMICAL RESEARCH

Sequence-Based Design of α/β-Peptide Foldamers That Mimic BH3 Domains

(2008) W. Seth Horne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Contemporary strategies for the stabilization of peptides in the α-helical conformation

(2008) Laura K Henchey et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Oligo(N-aryl glycines): A New Twist on Structured Peptoids

(2008) Neel H. Shah et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The genetics of the p53 pathway, apoptosis and cancer therapy

(2008) Alexei Vazquez et al.   NATURE REVIEWS DRUG DISCOVERY