Pathogen-Mediated Proteolysis of the Cell Death Regulator RIPK1 and the Host Defense Modulator RIPK2 in Human Aortic Endothelial Cells

Cross-Tolerization between Nod1 and Nod2 Signaling Results in Reduced Refractoriness to Bacterial Infection in Nod2-Deficient Macrophages

(2014) Y.-G. Kim et al.   JOURNAL OF IMMUNOLOGY

Bacterial Fimbriae Stimulate Proinflammatory Activation in the Endothelium through Distinct TLRs

(2014) M. Davey et al.   JOURNAL OF IMMUNOLOGY

PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis

(2011) Nan Zhang et al.   Autophagy

NOD-Like Receptor Activation by Outer Membrane Vesicles fromVibrio choleraeNon-O1 Non-O139 Strains Is Modulated by the Quorum-Sensing Regulator HapR

(2011) H. Bielig et al.   INFECTION AND IMMUNITY

Structures, Synthesis, and Human Nod1 Stimulation of Immunostimulatory Bacterial Peptidoglycan Fragments in the Environment

(2011) Yukari Fujimoto et al.   JOURNAL OF NATURAL PRODUCTS

The protein Nod2: An innate receptor more complex than previously assumed

(2010) Aurore Lecat et al.   BIOCHEMICAL PHARMACOLOGY

Virus Inhibition of RIP3-Dependent Necrosis

(2010) Jason W. Upton et al.   Cell Host & Microbe

Receptor-interacting protein (RIP) kinase family

(2010) Duanwu Zhang et al.   Cellular & Molecular Immunology

NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages

(2010) Michelle N. Brooks et al.   CELLULAR MICROBIOLOGY

Exit of intracellular Porphyromonas gingivalis from gingival epithelial cells is mediated by endocytic recycling pathway

(2010) Hiroki Takeuchi et al.   CELLULAR MICROBIOLOGY

High Antibody Levels to P. gingivalis in Cardiovascular Disease

(2010) S. Bohnstedt et al.   JOURNAL OF DENTAL RESEARCH

Pathogen-Mediated Inflammatory Atherosclerosis Is Mediated in Part via Toll-Like Receptor 2-Induced Inflammatory Responses

(2010) Chie Hayashi et al.   Journal of Innate Immunity

Orientia tsutsugamushi induced endothelial cell activation via the NOD1-IL-32 pathway

(2010) Kyung-Ah Cho et al.   MICROBIAL PATHOGENESIS

Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon’s knife to a meat chopper-like brutal degradation of proteins

(2010) Yonghua Guo et al.   PERIODONTOLOGY 2000

Staphylococcal Peptidoglycan Co-Localizes with Nod2 and TLR2 and Activates Innate Immune Response via Both Receptors in Primary Murine Keratinocytes

(2010) Maria Anna Müller-Anstett et al.   PLoS One

Mathematical Modelling of Cell-Fate Decision in Response to Death Receptor Engagement

(2010) Laurence Calzone et al.   PLoS Computational Biology

RIP Kinases at the Crossroads of Cell Death and Survival

(2009) Wim Declercq et al.   CELL

Expression and regulation of the NALP3 inflammasome complex in periodontal diseases

(2009) N. Bostanci et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2

(2009) Mathieu J.M. Bertrand et al.   IMMUNITY

RICK Promotes Inflammation and Lethality after Gram-Negative Bacterial Infection in Mice Stimulated with Lipopolysaccharide

(2009) J.-H. Park et al.   INFECTION AND IMMUNITY

Entry of Porphyromonas gingivalis Outer Membrane Vesicles into Epithelial Cells Causes Cellular Functional Impairment

(2009) N. Furuta et al.   INFECTION AND IMMUNITY

Porphyromonas gingivalis Outer Membrane Vesicles Enter Human Epithelial Cells via an Endocytic Pathway and Are Sorted to Lysosomal Compartments

(2009) N. Furuta et al.   INFECTION AND IMMUNITY

The Kinase Activity of Rip2 Determines Its Stability and Consequently Nod1- and Nod2-mediated Immune Responses

(2009) Chiara Nembrini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses

(2009) S. Lipinski et al.   JOURNAL OF CELL SCIENCE

Periodontitis and risk for atherosclerosis: an update on intervention trials

(2009) Maurizio S. Tonetti   JOURNAL OF CLINICAL PERIODONTOLOGY

NOD1 and NOD2 Mediate Sensing of Periodontal Pathogens

(2009) T. Okugawa et al.   JOURNAL OF DENTAL RESEARCH

Clathrin- and Dynamin-Dependent Endocytic Pathway Regulates Muramyl Dipeptide Internalization and NOD2 Activation

(2009) N. Marina-Garcia et al.   JOURNAL OF IMMUNOLOGY

Critical Role of Apoptotic Speck Protein Containing a Caspase Recruitment Domain (ASC) and NLRP3 in Causing Necrosis and ASC Speck Formation Induced by Porphyromonas gingivalis in Human Cells

(2009) M. T.-H. Huang et al.   JOURNAL OF IMMUNOLOGY

Quantitative detection of periodontopathic bacteria in atherosclerotic plaques from coronary arteries

(2009) E. Gaetti-Jardim et al.   JOURNAL OF MEDICAL MICROBIOLOGY

RIP2-β: A novel alternative mRNA splice variant of the receptor interacting protein kinase RIP2

(2009) Andreas Krieg et al.   MOLECULAR IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

The Ubiquitin-Editing Enzyme A20 Restricts Nucleotide-Binding Oligomerization Domain Containing 2-Triggered Signals

(2008) Osamu Hitotsumatsu et al.   IMMUNITY

Cytomegalovirus M45 Cell Death Suppression Requires Receptor-interacting Protein (RIP) Homotypic Interaction Motif (RHIM)-dependent Interaction with RIP1

(2008) Jason W. Upton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APorphyromonas gingivalistyrosine phosphatase is a multifunctional regulator of virulence attributes

(2008) Kazuhiko Maeda et al.   MOLECULAR MICROBIOLOGY

The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

(2008) Noula Shembade et al.   NATURE IMMUNOLOGY

Both cIAP1 and cIAP2 regulate TNF -mediated NF- B activation

(2008) D. J. Mahoney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

(2008) B. D. Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atheroprotective role of interleukin-6 in diet- and/or pathogen-associated atherosclerosis using an ApoE heterozygote murine model

(2007) Monika Madan et al.   ATHEROSCLEROSIS

Engagement of specific innate immune signaling pathways during Porphyromonas gingivalis induced chronic inflammation and atherosclerosis

(2007) Frank et al.   Frontiers in Bioscience-Landmark