The Cell Wall-Associated Mycolactone Polyketide Synthases Are Necessary but Not Sufficient for Mycolactone Biosynthesis

Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation

(2013) Laure Guenin-Macé et al.   JOURNAL OF CLINICAL INVESTIGATION

Essential Role of the Donor Acyl Carrier Protein in Stereoselective Chain Translocation to a Fully Reducing Module of the Nanchangmycin Polyketide Synthase

(2012) Xun Guo et al.   BIOCHEMISTRY

On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer

(2012) Kenneth D Doig et al.   BMC GENOMICS

Improved mycobacterial protein production using a Mycobacterium smegmatis groEL1ΔC expression strain

(2011) Elke E Noens et al.   BMC BIOTECHNOLOGY

Regulation of the 18 kDa heat shock protein in Mycobacterium ulcerans: an alpha-crystallin orthologue that promotes biofilm formation

(2010) Sacha J. Pidot et al.   MOLECULAR MICROBIOLOGY

Mycolactone Suppresses T Cell Responsiveness by Altering Both Early Signaling and Posttranslational Events

(2009) S. Boulkroun et al.   JOURNAL OF IMMUNOLOGY

Mycolactone Inhibits Monocyte Cytokine Production by a Posttranscriptional Mechanism

(2009) R. E. Simmonds et al.   JOURNAL OF IMMUNOLOGY

Immunosuppressive Signature of CutaneousMycobacterium ulceransInfection in the Peripheral Blood of Patients with Buruli Ulcer Disease

(2009) Richard Phillips et al.   JOURNAL OF INFECTIOUS DISEASES

Transfer, stable maintenance and expression of the mycolactone polyketide megasynthase mls genes in a recombination-impaired Mycobacterium marinum

(2009) J. L. Porter et al.   MICROBIOLOGY-SGM

Mycolactone Gene Expression Is Controlled by Strong SigA-Like Promoters with Utility in Studies of Mycobacterium ulcerans and Buruli Ulcer

(2009) Nicholas J. Tobias et al.   PLoS Neglected Tropical Diseases

Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones

(2008) Sacha J Pidot et al.   BMC GENOMICS

Localization of the ActIII actinorhodin polyketide ketoreductase to the cell wall

(2008) Xin-Ping Xu et al.   FEMS MICROBIOLOGY LETTERS

First report of a mycolactone-producingMycobacteriuminfection in fish agriculture in Belgium

(2008) Pieter Stragier et al.   FEMS MICROBIOLOGY LETTERS

Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria

(2008) Hui Hong et al.   NATURAL PRODUCT REPORTS

Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis

(2008) Petra Tafelmeyer et al.   PROTEOMICS

Mycolactone Diffuses from Mycobacterium ulcerans–Infected Tissues and Targets Mononuclear Cells in Peripheral Blood and Lymphoid Organs

(2008) Hui Hong et al.   PLoS Neglected Tropical Diseases