Dendritic Cell Immunoreceptor Is a New Target for Anti-AIDS Drug Development: Identification of DCIR/HIV-1 Inhibitors

DC-SIGN Antagonists, a Potential New Class of Anti-Infectives

(2012) M. Anderluh et al.   CURRENT MEDICINAL CHEMISTRY

HIV/AIDS: Recent Advances in Antiretroviral Agents

(2012) Georgios Nikolopoulos et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

A glycomimetic compound inhibits DC-SIGN-mediated HIV infection in cellular and cervical explant models

(2011) Angela Berzi et al.   AIDS

DCIR-mediated enhancement of HIV-1 infection requires the ITIM-associated signal transduction pathway

(2011) A. A. Lambert et al.   BLOOD

HIV-1 Escape from the CCR5 Antagonist Maraviroc Associated with an Altered and Less-Efficient Mechanism of gp120-CCR5 Engagement That Attenuates Macrophage Tropism

(2011) M. Roche et al.   JOURNAL OF VIROLOGY

A combination of polymorphic mutations in V3 loop of HIV-1 gp120 can confer noncompetitive resistance to maraviroc

(2011) Yuzhe Yuan et al.   VIROLOGY

A look at HIV journey

(2011) Fabien Blanchet et al.   Current Opinion in HIV and AIDS

Cardiovascular disease in HIV infection

(2011) Frank J Palella et al.   Current Opinion in HIV and AIDS

Early Events in Sexual Transmission of HIV and SIV and Opportunities for Interventions

(2010) Ashley T. Haase   Annual Review of Medicine

Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR

(2010) E. Klechevsky et al.   BLOOD

During HIV-1 infection most blood dendritic cells are not productively infected and can induce allogeneic CD4+ T cells clonal expansion

(2010) P. U. CAMERON et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Survey of immune-related, mannose/fucose-binding C-type lectin receptors reveals widely divergent sugar-binding specificities

(2010) R. T. Lee et al.   GLYCOBIOLOGY

Human Immunodeficiency Virus-1 Inhibition of Immunoamphisomes in Dendritic Cells Impairs Early Innate and Adaptive Immune Responses

(2010) Fabien P. Blanchet et al.   IMMUNITY

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

(2010) Nicolas Manel et al.   NATURE

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

HIV-1 Induces DCIR Expression in CD4+ T Cells

(2010) Alexandra A. Lambert et al.   PLoS Pathogens

Novel targets for anti-retroviral therapy

(2009) Sanjay Bhattacharya et al.   JOURNAL OF INFECTION

The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways

(2008) A. A. Lambert et al.   BLOOD

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-  production

(2008) F. Meyer-Wentrup et al.   BLOOD

DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production

(2008) Friederike Meyer-Wentrup et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Calculation of Molecular Lipophilicity: State-of-the-Art and Comparison of LogP Methods on more than 96,000 Compounds

(2008) Raimund Mannhold et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells

(2008) Noriyuki Fujikado et al.   NATURE MEDICINE