Multiple Sclerosis: Modulation of Toll-Like Receptor (TLR) Expression by Interferon-β Includes Upregulation of TLR7 in Plasmacytoid Dendritic Cells

Elevated type I interferon-like activity in a subset of multiple sclerosis patients: molecular basis and clinical relevance

(2012) Alexander Hundeshagen et al.   Journal of Neuroinflammation

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration

(2012) Sabrina M Lehmann et al.   NATURE NEUROSCIENCE

Treatment of Autoimmune Inflammation by a TLR7 Ligand Regulating the Innate Immune System

(2012) Tomoko Hayashi et al.   PLoS One

Beta-interferon for multiple sclerosis

(2011) Richard A. Rudick et al.   EXPERIMENTAL CELL RESEARCH

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse

(2011) Ana Longhini et al.   Journal of Neuroinflammation

Temporal relationship between environmental influenza A and Epstein–Barr viral infections and high multiple sclerosis relapse occurrence

(2011) Mervi Oikonen et al.   Multiple Sclerosis Journal

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Interferon-β inhibits toll-like receptor 9 processing in multiple sclerosis

(2010) Konstantin E. Balashov et al.   ANNALS OF NEUROLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

(2010) Sarah L. Jongbloed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The TLR7 agonist, imiquimod, increases IFN-β production and reduces the severity of experimental autoimmune encephalomyelitis

(2010) Kate O'Brien et al.   JOURNAL OF NEUROIMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-β-1b treatment in relapsing remitting MS

(2010) Robert H Goertsches et al.   PHARMACOGENOMICS

Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

(2009) Yasuhiro Itsui et al.   HEPATOLOGY

IFN- 1a Inhibits the Secretion of Th17-Polarizing Cytokines in Human Dendritic Cells via TLR7 Up-Regulation

(2009) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid Dendritic Cells in Multiple Sclerosis

(2009) Roberto Lande et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY