Functional Comparison of Human Adenomatous Polyposis Coli (APC) and APC-Like in Targeting Beta-Catenin for Degradation

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Directional Neuronal Migration Is Impaired in Mice Lacking Adenomatous Polyposis Coli 2

(2012) T. Shintani et al.   JOURNAL OF NEUROSCIENCE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

A Common Role for Various Human Truncated Adenomatous Polyposis Coli Isoforms in the Control of Beta-Catenin Activity and Cell Proliferation

(2012) Shree Harsha Vijaya Chandra et al.   PLoS One

Destruction Complex Function in the Wnt Signaling Pathway of Drosophila Requires Multiple Interactions Between Adenomatous Polyposis Coli 2 and Armadillo

(2011) E. Kunttas-Tatli et al.   GENETICS

APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerization of truncated APC

(2011) Jean Schneikert et al.   HUMAN MOLECULAR GENETICS

Cortical localization of APC2 plays a role in actin organization but not in Wnt signaling in Drosophila

(2011) M.-N. Zhou et al.   JOURNAL OF CELL SCIENCE

Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling

(2011) David M. Roberts et al.   MOLECULAR BIOLOGY OF THE CELL

Inactivation of the APC Gene Is Constant in Adrenocortical Tumors from Patients with Familial Adenomatous Polyposis but Not Frequent in Sporadic Adrenocortical Cancers

(2010) S. Gaujoux et al.   CLINICAL CANCER RESEARCH

Directed Microtubule Growth, +TIPs, and Kinesin-2 Are Required for Uniform Microtubule Polarity in Dendrites

(2010) Floyd J. Mattie et al.   CURRENT BIOLOGY

Severe polyposis in Apc1322Tmice is associated with submaximal Wnt signalling and increased expression of the stem cell markerLgr5

(2010) Annabelle Lewis et al.   GUT

Independent Interactions of Phosphorylated β-Catenin with E-Cadherin at Cell-Cell Contacts and APC at Cell Protrusions

(2010) Maree C. Faux et al.   PLoS One

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

The Apc1322T Mouse Develops Severe Polyposis Associated With Submaximal Nuclear β-Catenin Expression

(2009) Patrick Pollard et al.   GASTROENTEROLOGY

Key Role for Activin B in Cellular Transformation after Loss of the von Hippel-Lindau Tumor Suppressor

(2009) I. Wacker et al.   MOLECULAR AND CELLULAR BIOLOGY

Contribution of the 15 amino acid repeats of truncated APC to β-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients

(2009) E M Kohler et al.   ONCOGENE

Genetic Mechanisms in Apc-Mediated Mammary Tumorigenesis

(2009) Mari Kuraguchi et al.   PLoS Genetics

Cell regulation by the Apc protein

(2008) Brooke M McCartney et al.   CURRENT OPINION IN CELL BIOLOGY

Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours

(2008) E. M. Kohler et al.   HUMAN MOLECULAR GENETICS

 -Catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours

(2008) E. M. Kohler et al.   HUMAN MOLECULAR GENETICS

Novel self-association of the APC molecule affects APC clusters and cell migration

(2008) Z. Li et al.   JOURNAL OF CELL SCIENCE

APC Is Essential for Targeting Phosphorylated β-Catenin to the SCFβ-TrCP Ubiquitin Ligase

(2008) YunYun Su et al.   MOLECULAR CELL