Contribution of the 15 amino acid repeats of truncated APC to β-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients

The Apc1322T Mouse Develops Severe Polyposis Associated With Submaximal Nuclear β-Catenin Expression

(2009) Patrick Pollard et al.   GASTROENTEROLOGY

Genetic Mechanisms in Apc-Mediated Mammary Tumorigenesis

(2009) Mari Kuraguchi et al.   PLoS Genetics

A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis

(2009) Claudia Gaspar et al.   PLoS Genetics

Cell regulation by the Apc protein

(2008) Brooke M McCartney et al.   CURRENT OPINION IN CELL BIOLOGY

Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo

(2008) Wynne Peterson-Nedry et al.   DEVELOPMENTAL BIOLOGY

Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours

(2008) E. M. Kohler et al.   HUMAN MOLECULAR GENETICS

 -Catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours

(2008) E. M. Kohler et al.   HUMAN MOLECULAR GENETICS

Difference in characteristics ofAPC mutations between colonic and extracolonic tumors of FAP patients: Variations with phenotype

(2008) Michiko Miyaki et al.   INTERNATIONAL JOURNAL OF CANCER

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

Functional Characterization of the Novel APC N1026S Variant Associated With Attenuated Familial Adenomatous Polyposis

(2007) Mireia Menéndez et al.   GASTROENTEROLOGY