Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts

The Crosstalk of mTOR/S6K1 and Hedgehog Pathways

(2012) Yan Wang et al.   CANCER CELL

Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness

(2012) Enza Lonardo et al.   CELL CYCLE

Drugs in preclinical and early-stage clinical development for pancreatic cancer

(2012) Swapna Asuthkar et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy

(2011) Enza Lonardo et al.   Cell Stem Cell

c-Met Is a Marker of Pancreatic Cancer Stem Cells and Therapeutic Target

(2011) Chenwei Li et al.   GASTROENTEROLOGY

In vitro and in vivo characterization of a novel hedgehog signaling antagonist in human glioblastoma cell lines

(2011) Pietro Ferruzzi et al.   INTERNATIONAL JOURNAL OF CANCER

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

(2011) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of Ataxia Telangiectasia- and Rad3 -Related Function Abrogates the In Vitro and In Vivo Tumorigenicity of Human Colon Cancer Cells Through Depletion of the CD133+ Tumor-Initiating Cell Fraction

(2011) Eike Gallmeier et al.   STEM CELLS

Long circulation and cytotoxicity of PEGylated gemcitabine and its potential for the treatment of pancreatic cancer

(2010) Mallaredy Vandana et al.   BIOMATERIALS

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Pancreatic cancer stem cells - update and future perspectives

(2010) Enza Lonardo et al.   Molecular Oncology

Cancer stem cells in solid tumors

(2010) Patrick C. Hermann et al.   SEMINARS IN CANCER BIOLOGY

In vivo activity of gemcitabine-loaded PEGylated small unilamellar liposomes against pancreatic cancer

(2009) Donato Cosco et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Combined Targeted Treatment to Eliminate Tumorigenic Cancer Stem Cells in Human Pancreatic Cancer

(2009) Maria–Theresa Mueller et al.   GASTROENTEROLOGY

Consensus Report of the National Cancer Institute Clinical Trials Planning Meeting on Pancreas Cancer Treatment

(2009) Philip A. Philip et al.   JOURNAL OF CLINICAL ONCOLOGY

A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development

(2009) A. Jimeno et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE