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Hedgehog Target Genes: Mechanisms of Carcinogenesis Induced by Aberrant Hedgehog Signaling Activation

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Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

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Brain tumor treatment increases the number of cancer stem-like cells

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Combined Targeted Treatment to Eliminate Tumorigenic Cancer Stem Cells in Human Pancreatic Cancer

(2009) Maria–Theresa Mueller et al.   GASTROENTEROLOGY

Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines

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Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

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Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

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(2009) Yu Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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Hedgehog signalling in endocrine development and disease

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