Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation

A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness

(2011) E. D. Gordon et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Increased arginase activity contributes to airway remodelling in chronic allergic asthma

(2011) H. Maarsingh et al.   EUROPEAN RESPIRATORY JOURNAL

Immune modulation for treatment of allergic disease

(2011) Tran-Hoai T. Nguyen et al.   IMMUNOLOGICAL REVIEWS

Macrophages in Allergic Asthma: Fine-Tuning Their Pro- and Anti-Inflammatory Actions for Disease Resolution

(2011) Ana Paula Moreira et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Obstacles and opportunities for understanding macrophage polarization

(2011) P. J. Murray et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Binding of α,α-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design

(2011) Monica Ilies et al.   JOURNAL OF MEDICINAL CHEMISTRY

Direct inhibition of arginase attenuated airway allergic reactions and inflammation in a Dermatophagoides farinae-induced NC/Nga mouse model

(2010) Noriko Takahashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inhibition of human arginase I by substrate and product analogues

(2010) Luigi Di Costanzo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Schistosoma mansoni antigens modulate the allergic response in a murine model of ovalbumin-induced airway inflammation

(2010) L. S. Cardoso et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Impaired pulmonary immunity post-bone marrow transplant

(2010) Stephanie M. Coomes et al.   IMMUNOLOGIC RESEARCH

Arginase I Suppresses IL-12/IL-23p40-Driven Intestinal Inflammation during Acute Schistosomiasis

(2010) D. R. Herbert et al.   JOURNAL OF IMMUNOLOGY

Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling

(2010) J. E. Qualls et al.   Science Signaling

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma

(2009) Michelle L. North et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice

(2009) Kathryn A Niese et al.   BMC IMMUNOLOGY

Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives

(2009) Harm Maarsingh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Recent advances in arginine metabolism: roles and regulation of the arginases

(2009) Sidney M Morris Jr   BRITISH JOURNAL OF PHARMACOLOGY

Pulmonary fibrosis: pathogenesis, etiology and regulation

(2009) M S Wilson et al.   Mucosal Immunology

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

(2009) A. I. Caceres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

(2009) John T. Pesce et al.   PLoS Pathogens

Arginase Inhibition Protects against Allergen-induced Airway Obstruction, Hyperresponsiveness, and Inflammation

(2008) Harm Maarsingh et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evolution of the arginase fold and functional diversity

(2008) D. P. Dowling et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Arginine homeostasis in allergic asthma

(2008) Harm Maarsingh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Schistosoma mansoni Antigens Modulate Experimental Allergic Asthma in a Murine Model: a Major Role for CD4+ CD25+ Foxp3+ T Cells Independent of Interleukin-10

(2008) L. G. G. Pacifico et al.   INFECTION AND IMMUNITY

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY

Cationic Amino Acid Transporter-2 Regulates Immunity by Modulating Arginase Activity

(2008) Robert W. Thompson et al.   PLoS Pathogens