Characterization of Cognitive Deficits in Rats Overexpressing Human Alpha-Synuclein in the Ventral Tegmental Area and Medial Septum Using Recombinant Adeno-Associated Viral Vectors

Cognitive deficits in a mouse model of pre-manifest Parkinson’s disease

(2012) Iddo Magen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Impairment of the septal cholinergic neurons in MPTP-treated A30P α-synuclein mice

(2012) Éva M. Szegő et al.   NEUROBIOLOGY OF AGING

Impaired neurotransmission caused by overexpression of  -synuclein in nigral dopamine neurons

(2012) M. Lundblad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Syn Suppression Reverses Synaptic and Memory Defects in a Mouse Model of Dementia with Lewy Bodies

(2011) Y. Lim et al.   JOURNAL OF NEUROSCIENCE

Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein

(2011) Hoa A. Lam et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice

(2011) Éva M. Szegő et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons

(2011) M. Decressac et al.   NEUROBIOLOGY OF DISEASE

Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease

(2011) Eliezer Masliah et al.   PLoS One

Proteinase K-resistant α-synuclein is deposited in presynapses in human Lewy body disease and A53T α-synuclein transgenic mice

(2010) Kunikazu Tanji et al.   ACTA NEUROPATHOLOGICA

Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease

(2010) James B Koprich et al.   Molecular Neurodegeneration

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

Presynaptic dopaminergic compartment determines the susceptibility to L-DOPA-induced dyskinesia in rats

(2010) A. Ulusoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The epidemiology of dementia associated with Parkinson disease

(2009) Dag Aarsland et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Dose Optimization for Long-term rAAV-mediated RNA Interference in the Nigrostriatal Projection Neurons

(2009) Ayse Ulusoy et al.   MOLECULAR THERAPY

Functional Convergence of Dopaminergic and Cholinergic Input Is Critical for Hippocampus-Dependent Working Memory

(2008) L. A. B. Wisman et al.   JOURNAL OF NEUROSCIENCE

Neurodegeneration and Motor Dysfunction in a Conditional Model of Parkinson's Disease

(2008) S. Nuber et al.   JOURNAL OF NEUROSCIENCE