Lysyl Oxidase Is Downregulated by the EWS/FLI1 Oncoprotein and Its Propeptide Domain Displays Tumor Supressor Activities in Ewing Sarcoma Cells

Ewing Sarcoma: Clinical State-of-the-Art

(2012) Jenny Potratz et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY

miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy

(2011) Fumihiko Nakatani et al.   JOURNAL OF PATHOLOGY

STEAP1 Is Associated with the Invasive and Oxidative Stress Phenotype of Ewing Tumors

(2011) T. G. P. Grunewald et al.   MOLECULAR CANCER RESEARCH

Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma

(2011) J Ban et al.   ONCOGENE

Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development

(2011) Claudio De Vito et al.   PLoS One

Characterization of Recombinant Lysyl Oxidase Propeptide

(2010) Siddharth R. Vora et al.   BIOCHEMISTRY

The molecular pathogenesis of Ewing sarcoma

(2010) Carlos Mackintosh et al.   CANCER BIOLOGY & THERAPY

A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature

(2010) Jeffrey D. Hancock et al.   CELL CYCLE

Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis

(2010) Chengyin Min et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Recent advances in the molecular pathogenesis of Ewing's sarcoma

(2010) E C Toomey et al.   ONCOGENE

Downstream EWS/FLI1 - upstream Ewing's sarcoma

(2010) Heinrich Kovar   Genome Medicine

Stable interference of EWS–FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target

(2009) D Herrero-Martín et al.   BRITISH JOURNAL OF CANCER

Advances in Ewing's Sarcoma Research: Where Are We Now and What Lies Ahead?

(2009) J. L. Ordonez et al.   CANCER RESEARCH

The EWS/FLI1 oncogenic protein inhibits expression of the Wnt inhibitor DICKKOPF-1 gene and antagonizes β-catenin/TCF-mediated transcription

(2009) Diego Navarro et al.   CARCINOGENESIS

GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance

(2009) W Luo et al.   ONCOGENE

Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling

(2009) A H Palamakumbura et al.   ONCOGENE

A Molecular Function Map of Ewing's Sarcoma

(2009) Maximilian Kauer et al.   PLoS One

EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation

(2009) G. H. S. Richter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EWS-FLI1 Suppresses NOTCH-Activated p53 in Ewing's Sarcoma

(2008) J. Ban et al.   CANCER RESEARCH

The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130Casin Breast Cancer Cells

(2008) Yingshe Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells

(2008) E García-Aragoncillo et al.   ONCOGENE

EWS/FLI Mediates Transcriptional Repression via NKX2.2 during Oncogenic Transformation in Ewing's Sarcoma

(2008) Leah A. Owen et al.   PLoS One

Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation

(2007) Paola A. Hurtado et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS