Machine Learning Prediction of Cancer Cell Sensitivity to Drugs Based on Genomic and Chemical Properties

CDRUG: a web server for predicting anticancer activity of chemical compounds

(2012) Gong-Hua Li et al.   BIOINFORMATICS

CellMiner: A Web-Based Suite of Genomic and Pharmacologic Tools to Explore Transcript and Drug Patterns in the NCI-60 Cell Line Set

(2012) W. C. Reinhold et al.   CANCER RESEARCH

Large-Scale Elucidation of Drug Response Pathways in Humans

(2012) Yael Silberberg et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Cancer biomarkers: selecting the right drug for the right patient

(2012) Gary J. Kelloff et al.   NATURE REVIEWS DRUG DISCOVERY

Editorial: Computational methods for drug repurposing

(2011) P. Sanseau et al.   BRIEFINGS IN BIOINFORMATICS

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

Subtype and pathway specific responses to anticancer compounds in breast cancer

(2011) L. M. Heiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying Causal Genes and Dysregulated Pathways in Complex Diseases

(2011) Yoo-Ah Kim et al.   PLoS Computational Biology

Simplistic pathways or complex networks?

(2010) Claus Jørgensen et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Ranking Chemical Structures for Drug Discovery: A New Machine Learning Approach

(2010) Shivani Agarwal et al.   Journal of Chemical Information and Modeling

PaDEL-descriptor: An open source software to calculate molecular descriptors and fingerprints

(2010) Chun Wei Yap   JOURNAL OF COMPUTATIONAL CHEMISTRY

Integrative Analysis of Proteomic Signatures, Mutations, and Drug Responsiveness in the NCI 60 Cancer Cell Line Set

(2010) E. S. Park et al.   MOLECULAR CANCER THERAPEUTICS

DEGAS: De Novo Discovery of Dysregulated Pathways in Human Diseases

(2010) Igor Ulitsky et al.   PLoS One

Using Expression and Genotype to Predict Drug Response in Yeast

(2009) Douglas M. Ruderfer et al.   PLoS One

A modular approach for integrative analysis of large-scale gene-expression and drug-response data

(2008) Zoltán Kutalik et al.   NATURE BIOTECHNOLOGY