The Type II Hsp40 Sis1 Cooperates with Hsp70 and the E3 Ligase Ubr1 to Promote Degradation of Terminally Misfolded Cytosolic Protein
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Type II Hsp40 Sis1 Cooperates with Hsp70 and the E3 Ligase Ubr1 to Promote Degradation of Terminally Misfolded Cytosolic Protein
Authors
Keywords
-
Journal
PLoS One
Volume 8, Issue 1, Pages e52099
Publisher
Public Library of Science (PLoS)
Online
2013-01-17
DOI
10.1371/journal.pone.0052099
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation
- (2012) Juliane Winkler et al. JOURNAL OF CELL BIOLOGY
- Compartmentalization of superoxide dismutase 1 (SOD1G93A) aggregates determines their toxicity
- (2012) S. J. Weisberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hsp42 is required for sequestration of protein aggregates into deposition sites inSaccharomyces cerevisiae
- (2011) Sebastian Specht et al. JOURNAL OF CELL BIOLOGY
- Disorder Targets Misorder in Nuclear Quality Control Degradation: A Disordered Ubiquitin Ligase Directly Recognizes Its Misfolded Substrates
- (2011) Joel C. Rosenbaum et al. MOLECULAR CELL
- A Nucleus-based Quality Control Mechanism for Cytosolic Proteins
- (2010) Rupali Prasad et al. MOLECULAR BIOLOGY OF THE CELL
- Ubr1 and Ubr2 Function in a Quality Control Pathway for Degradation of Unfolded Cytosolic Proteins
- (2010) Nadinath B. Nillegoda et al. MOLECULAR BIOLOGY OF THE CELL
- The endoplasmic reticulum–associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3–dependent degradation of nascent CFTRΔF508
- (2010) Diane E. Grove et al. MOLECULAR BIOLOGY OF THE CELL
- The HSP70 chaperone machinery: J proteins as drivers of functional specificity
- (2010) Harm H. Kampinga et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Molecular chaperones antagonize proteotoxicity by differentially modulating protein aggregation pathways
- (2010) Peter M. Douglas et al. Prion
- Reciprocal Efficiency of RNQ1 and Polyglutamine Detoxification in the Cytosol and Nucleus
- (2009) Peter M. Douglas et al. MOLECULAR BIOLOGY OF THE CELL
- Inefficient Quality Control of Thermosensitive Proteins on the Plasma Membrane
- (2009) Michael J. Lewis et al. PLoS One
- Identification of a consensus motif in substrates bound by a Type I Hsp40
- (2009) P. Kota et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1
- (2009) J. W. Heck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions
- (2008) James Shorter et al. EMBO JOURNAL
- Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1
- (2008) Frederik Eisele et al. FEBS LETTERS
- The Type I Hsp40 Ydj1 Utilizes a Farnesyl Moiety and Zinc Finger-like Region to Suppress Prion Toxicity
- (2008) Daniel W. Summers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery
- (2008) Meredith Boyle Metzger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conserved Central Domains Control the Quaternary Structure of Type I and Type II Hsp40 Molecular Chaperones
- (2008) Carlos H.I. Ramos et al. JOURNAL OF MOLECULAR BIOLOGY
- In Vivo Monitoring of the Prion Replication Cycle Reveals a Critical Role for Sis1 in Delivering Substrates to Hsp104
- (2008) Kimberly A. Tipton et al. MOLECULAR CELL
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- Specificity of the J-protein Sis1 in the propagation of 3 yeast prions
- (2008) T. Higurashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chaperone-dependent amyloid assembly protects cells from prion toxicity
- (2008) P. M. Douglas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started