Constitutive CCND1/CDK2 Activity Substitutes for p53 Loss, or MYC or Oncogenic RAS Expression in the Transformation of Human Mammary Epithelial Cells

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

TGF-  signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells

(2011) R. Cipriano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tipping the Balance: Cdk2 Enables Myc to Suppress Senescence

(2010) P. Hydbring et al.   CANCER RESEARCH

Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures

(2010) H. Mizuno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells

(2009) J. C. Garbe et al.   CANCER RESEARCH

Stepwise DNA Methylation Changes Are Linked to Escape from Defined Proliferation Barriers and Mammary Epithelial Cell Immortalization

(2009) P. Novak et al.   CANCER RESEARCH

A Novel Class of Cyclin-dependent Kinase Inhibitors Identified by Molecular Docking Act through a Unique Mechanism

(2009) Patrick Corsino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

(2009) P. Hydbring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA