Native Tertiary Structure and Nucleoside Modifications Suppress tRNA’s Intrinsic Ability to Activate the Innate Immune Sensor PKR
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Native Tertiary Structure and Nucleoside Modifications Suppress tRNA’s Intrinsic Ability to Activate the Innate Immune Sensor PKR
Authors
Keywords
-
Journal
PLoS One
Volume 8, Issue 3, Pages e57905
Publisher
Public Library of Science (PLoS)
Online
2013-03-05
DOI
10.1371/journal.pone.0057905
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity
- (2012) Stefanie Gehrig et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Activation of PKR by RNA misfolding: HDV ribozyme dimers activate PKR
- (2012) L. A. Heinicke et al. RNA
- Mechanistic characterization of the 5'-triphosphate-dependent activation of PKR: Lack of 5'-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD
- (2012) R. Toroney et al. RNA
- A brilliant disguise for self RNA: 5’-end and internal modifications of primary transcripts suppress elements of innate immunity
- (2011) Subba Rao Nallagatla et al. RNA Biology
- RNA helical imperfections regulate activation of the protein kinase PKR: Effects of bulge position, size, and geometry
- (2011) L. A. Heinicke et al. RNA
- Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis
- (2010) Takahisa Nakamura et al. CELL
- Regulation of innate immunity through RNA structure and the protein kinase PKR
- (2010) Subba Rao Nallagatla et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Expansion of CUG RNA repeats causes stress and inhibition of translation in myotonic dystrophy 1 (DM1) cells
- (2010) Claudia Huichalaf et al. FASEB JOURNAL
- Orchestration of the Activation of Protein Kinase R by the RNA-Binding Motif
- (2010) Anthony J. Sadler JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- The Role of Protein Kinase R in the Interferon Response
- (2010) Agnieszka Pindel et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Regulation of PKR by HCV IRES RNA: Importance of Domain II and NS5A
- (2010) Rebecca Toroney et al. JOURNAL OF MOLECULAR BIOLOGY
- The crystal structure of unmodified tRNA Phe from Escherichia coli
- (2010) Robert T. Byrne et al. NUCLEIC ACIDS RESEARCH
- Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
- (2010) Bart R. Anderson et al. NUCLEIC ACIDS RESEARCH
- Translational insensitivity to potent activation of PKR by HCV IRES RNA
- (2009) Takashi Shimoike et al. ANTIVIRAL RESEARCH
- Analysis of PKR Structure by Small-Angle Scattering
- (2009) Jennifer VanOudenhove et al. JOURNAL OF MOLECULAR BIOLOGY
- RNA Dimerization Promotes PKR Dimerization and Activation
- (2009) Laurie A. Heinicke et al. JOURNAL OF MOLECULAR BIOLOGY
- Inhibition of Protein Kinase R Activation and Upregulation of GADD34 Expression Play a Synergistic Role in Facilitating Coronavirus Replication by Maintaining De Novo Protein Synthesis in Virus-Infected Cells
- (2009) X. Wang et al. JOURNAL OF VIROLOGY
- Dynamic refolding of IFN-γ mRNA enables it to function as PKR activator and translation template
- (2009) Smadar Cohen-Chalamish et al. Nature Chemical Biology
- Recognition of viral nucleic acids in innate immunity
- (2009) Mitsutoshi Yoneyama et al. REVIEWS IN MEDICAL VIROLOGY
- Influenza B Virus Ribonucleoprotein Is a Potent Activator of the Antiviral Kinase PKR
- (2009) Bianca Dauber et al. PLoS Pathogens
- A Disease-causing Point Mutation in Human Mitochondrial tRNAMetResults in tRNA Misfolding Leading to Defects in Translational Initiation and Elongation
- (2008) Christie N. Jones et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanism of PKR Activation by dsRNA
- (2008) Peter A. Lemaire et al. JOURNAL OF MOLECULAR BIOLOGY
- Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner
- (2008) S. R. Nallagatla et al. RNA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now