Epithelial Uptake of Flagella Initiates Proinflammatory Signaling

Control of Pseudomonas aeruginosa in the Lung Requires the Recognition of Either Lipopolysaccharide or Flagellin

(2014) R. Ramphal et al.   JOURNAL OF IMMUNOLOGY

Airway Epithelial Expression of TLR5 Is Downregulated in Healthy Smokers and Smokers with Chronic Obstructive Pulmonary Disease

(2012) R. Wang et al.   JOURNAL OF IMMUNOLOGY

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Cystic fibrosis: a mucosal immunodeficiency syndrome

(2012) Taylor Sitarik Cohen et al.   NATURE MEDICINE

The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens

(2012) Rhonda H Wilson et al.   NATURE MEDICINE

Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis

(2012) Anthony Tang et al.   PLoS One

A Crucial Role of Flagellin in the Induction of Airway Mucus Production by Pseudomonas aeruginosa

(2012) Fatima Ben Mohamed et al.   PLoS One

Toll-like receptor 5 (TLR5), IL-1  secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing

(2012) D. Descamps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of TLR5-Flagellin Recognition and Signaling

(2012) S.-i. Yoon et al.   SCIENCE

Pseudomonas aeruginosa Pili and Flagella Mediate Distinct Binding and Signaling Events at the Apical and Basolateral Surface of Airway Epithelium

(2012) Iwona Bucior et al.   PLoS Pathogens

Pneumonia Due to Pseudomonas aeruginosa

(2011) Shigeki Fujitani et al.   CHEST

The role of the NLRP3 Inflammasome in the pathogenesis of airway disease

(2011) Mark A. Birrell et al.   PHARMACOLOGY & THERAPEUTICS

Luminal-Applied Flagellin Is Internalized by Polarized Intestinal Epithelial Cells and Elicits Immune Responses via the TLR5 Dependent Mechanism

(2011) Tonyia Eaves-Pyles et al.   PLoS One

Streptococcus pneumoniae DNA Initiates Type I Interferon Signaling in the Respiratory Tract

(2011) D. Parker et al.   mBio

Step-Wise Loss of Bacterial Flagellar Torsion Confers Progressive Phagocytic Evasion

(2011) Rustin R. Lovewell et al.   PLoS Pathogens

Pseudomonas aeruginosa Evasion of Phagocytosis Is Mediated by Loss of Swimming Motility and Is Independent of Flagellum Expression

(2010) E. Amiel et al.   INFECTION AND IMMUNITY

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Toll-like receptor 5 in the innate immune response to acute P. aeruginosa pneumonia

(2009) Amy E. Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TLR2-Induced Calpain Cleavage of Epithelial Junctional Proteins Facilitates Leukocyte Transmigration

(2009) Jarin Chun et al.   Cell Host & Microbe

Rhamnolipid-induced shedding of flagellin fromPseudomonas aeruginosaprovokes hBD-2 and IL-8 response in human keratinocytes

(2009) Ulrich Gerstel et al.   CELLULAR MICROBIOLOGY

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin

(2009) Laure Janot et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The type III secretion system of Pseudomonas aeruginosa: infection by injection

(2009) Alan R. Hauser   NATURE REVIEWS MICROBIOLOGY

Pseudomonas aeruginosa LPS or Flagellin Are Sufficient to Activate TLR-Dependent Signaling in Murine Alveolar Macrophages and Airway Epithelial Cells

(2009) Eloïse Raoust et al.   PLoS One

Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs

(2009) M. Makam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudomonas aeruginosa activates caspase 1 through Ipaf

(2008) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA