Holothurian Glycosaminoglycan Inhibits Metastasis and Thrombosis via Targeting of Nuclear Factor-κB/Tissue Factor/Factor Xa Pathway in Melanoma B16F10 Cells

PMA-induced GCMa phosphorylation stimulates its transcriptional activity and degradation

(2012) Yuko Yasui et al.   BIOMEDICAL RESEARCH-TOKYO

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

(2012) A. M. Gil-Bernabe et al.   BLOOD

Dithiolethiones Inhibit NF- B Activity via Covalent Modification in Human Estrogen Receptor-Negative Breast Cancer

(2012) C. H. Switzer et al.   CANCER RESEARCH

Inhibitory effect of non-anticoagulant heparin (S-NACH) on pancreatic cancer cell adhesion and metastasis in human umbilical cord vessel segment and in mouse model

(2012) Thangirala Sudha et al.   CLINICAL & EXPERIMENTAL METASTASIS

Interferon-γ biphasically regulates angiotensinogen expression via a JAK-STAT pathway and suppressor of cytokine signaling 1 (SOCS1) in renal proximal tubular cells

(2012) Ryousuke Satou et al.   FASEB JOURNAL

Tissue factor expression determines tumour cell coagulation kinetics

(2012) J. WELSH et al.   International Journal of Laboratory Hematology

Piceatannol Suppresses Breast Cancer Cell Invasion through the Inhibition of MMP-9: Involvement of PI3K/AKT and NF-κB Pathways

(2012) Hyun Suk Ko et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM-1-PI3K-NF-κB pathway

(2012) Vanesa Gómez-Piña et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The role of the Janus kinase family/signal transducer and activator of transcription signaling pathway in fibrotic renal disease

(2012) Futoshi Matsui et al.   JOURNAL OF SURGICAL RESEARCH

Inhibition of Specific NF-κB Activity Contributes to the Tumor Suppressor Function of 14-3-3σ in Breast Cancer

(2012) Julia Inglés-Esteve et al.   PLoS One

PMA induces GCMa phosphorylation and alters its stability via the PKC- and ERK-dependent pathway

(2011) Yuko Yasui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ERK/NF-κB signaling pathway

(2011) Chih-Hsin Tang et al.   BIOCHEMICAL PHARMACOLOGY

Pancreatic cancer cell and microparticle procoagulant surface characterization

(2011) Katherine R. Yates et al.   BLOOD COAGULATION & FIBRINOLYSIS

Depletion of tissue factor suppresses hepatic metastasis and tumor growth in colorectal cancer via the downregulation of MMPs and the induction of autophagy and apoptosis

(2011) Maolin Tian et al.   CANCER BIOLOGY & THERAPY

γ-Actin regulates cell migration and modulates the ROCK signaling pathway

(2011) Michael S. Y. Shum et al.   FASEB JOURNAL

Antimetastatic potential of cardiotoxin III involves inactivation of PI3K/Akt and p38 MAPK signaling pathways in human breast cancer MDA-MB-231 cells

(2011) Kuei-Li Lin et al.   LIFE SCIENCES

Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-κB in colon cancer cells

(2011) Suboj Babykutty et al.   MOLECULAR CARCINOGENESIS

Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling

(2011) Wei Tan et al.   NATURE

Clotting Factor Deficiency in Early Trauma-Associated Coagulopathy

(2011) Sandro B. Rizoli et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Inhibiting NF-κB activation by small molecules as a therapeutic strategy

(2010) Subash C. Gupta et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Tissue factor as a novel marker for detection of circulating cancer cells

(2010) LL Otero et al.   BIOMARKERS

Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure

(2010) N. I. Popescu et al.   BLOOD

Acidic mucopolysaccharide from holothuria leucospilota has antitumor effect by inhibiting angiogenesis and tumor cell invasion in vivo and in vitro

(2010) Weiwei Zhang et al.   CANCER BIOLOGY & THERAPY

Tissue factor pathway inhibitor 2 (TFPI2) is frequently silenced by aberrant promoter hypermethylation in gastric cancer

(2010) Hisashi Takada et al.   CANCER GENETICS AND CYTOGENETICS

Fucosylated chondroitin sulfate inhibits plasma thrombin generation via targeting of the factor IXa heparin-binding exosite

(2009) Y. Buyue et al.   BLOOD

Self-production of tissue factor-coagulation factor VII complex by ovarian cancer cells

(2009) N Yokota et al.   BRITISH JOURNAL OF CANCER

Platelets and fibrinogen facilitate each other in protecting tumor cells from natural killer cytotoxicity

(2009) Sheng Zheng et al.   CANCER SCIENCE

Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal–epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells

(2009) I Fon Bambang et al.   LABORATORY INVESTIGATION

mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling

(2009) L.-A. Julien et al.   MOLECULAR AND CELLULAR BIOLOGY

Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis

(2009) M Petersen et al.   ONCOGENE

Metastasis and AKT activation

(2008) Shijie Sheng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Immune manipulation of advanced breast cancer: An interpretative model of the relationship between immune system and tumor cell biology

(2008) Andrea Nicolini et al.   MEDICINAL RESEARCH REVIEWS