Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid

RNAi screening of the kinome with cytarabine in leukemias

(2012) R. Tibes et al.   BLOOD

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

Clinical Applications of Epigenetic Markers and Epigenetic Profiling in Myeloid Malignancies

(2012) Michael A. McDevitt   SEMINARS IN ONCOLOGY

Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia

(2011) E McCormack et al.   LEUKEMIA

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

Intensive chemotherapy does not benefit most older patients (age 70 years or older) with acute myeloid leukemia

(2010) H. Kantarjian et al.   BLOOD

Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or Raltitrexed

(2010) Elena Di Gennaro et al.   CANCER BIOLOGY & THERAPY

Serologic Markers of Effective Tumor Immunity against Chronic Lymphocytic Leukemia Include Nonmutated B-Cell Antigens

(2010) O. Marina et al.   CANCER RESEARCH

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

Temporal proteome profiling of taxol-induced mitotic arrest and apoptosis

(2010) Vibeke H. Bull et al.   ELECTROPHORESIS

The histone demethylase UTX enables RB-dependent cell fate control

(2010) J. K. Wang et al.   GENES & DEVELOPMENT

Histone deacetylase inhibitors for the treatment of myelodysplastic syndrome and acute myeloid leukemia

(2010) A Quintás-Cardama et al.   LEUKEMIA

Lentinan: Hematopoietic, Immunological, and Efficacy Studies in a Syngeneic Model of Acute Myeloid Leukemia

(2010) Emmet McCormack et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Long-term efficacy of valproate versus lamotrigine in treatment of idiopathic generalized epilepsies in children and adolescents

(2010) Maria Mazurkiewicz-Bełdzińska et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Mutations of polycomb-associated geneASXL1in myelodysplastic syndromes and chronic myelomonocytic leukaemia

(2009) Véronique Gelsi-Boyer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Proteomic and Genetic Approaches Identify Syk as an AML Target

(2009) Cynthia K. Hahn et al.   CANCER CELL

A histone code for the DNA damage response in mammalian cells?

(2009) Armelle Corpet et al.   EMBO JOURNAL

Global networks of functional coupling in eukaryotes from comprehensive data integration

(2009) A. Alexeyenko et al.   GENOME RESEARCH

The Phosphatidylinositol 3-Kinase/Akt Pathway Regulates Transforming Growth Factor-β Signaling by Destabilizing Ski and Inducing Smad7

(2009) Arja M. Band et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic Lethal Genetic Interactions That Decrease Somatic Cell Proliferation in Caenorhabditis elegans Identify the Alternative RFCCTF18 as a Candidate Cancer Drug Target

(2009) Jessica McLellan et al.   MOLECULAR BIOLOGY OF THE CELL

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

(2009) Gijs van Haaften et al.   NATURE GENETICS

Functional proteomic profiling of AML predicts response and survival

(2008) S. M. Kornblau et al.   BLOOD

Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death

(2008) G. Gausdal et al.   BLOOD

Valproic acid as epigenetic cancer drug: Preclinical, clinical and transcriptional effects on solid tumors

(2008) Alfonso Duenas-Gonzalez et al.   CANCER TREATMENT REVIEWS

A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid

(2008) Anita Ryningen et al.   LEUKEMIA RESEARCH