Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion

Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: metanalysis and systematic review of the literature

(2012) Giovanni Corso et al.   BMC CANCER

TGF- -induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

(2012) S. Lamouille et al.   JOURNAL OF CELL SCIENCE

Rho GTPase signaling in the development of colorectal cancer

(2012) Fernanda Leve et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

E-Cadherin Destabilization Accounts for the Pathogenicity of Missense Mutations in Hereditary Diffuse Gastric Cancer

(2012) Joana Simões-Correia et al.   PLoS One

A Membrane Fusion Protein αSNAP Is a Novel Regulator of Epithelial Apical Junctions

(2012) Nayden G. Naydenov et al.   PLoS One

Akt/PKB-Mediated Phosphorylation of Twist1 Promotes Tumor Metastasis via Mediating Cross-Talk between PI3K/Akt and TGF-β Signaling Axes

(2012) Gongda Xue et al.   Cancer Discovery

The MLH12101C>A (Q701K) variant increases the risk of gastric cancer in Chinese males

(2011) Wenxian Zhi et al.   BMC GASTROENTEROLOGY

Renal cancer and pneumothorax risk in Birt–Hogg–Dubé syndrome; an analysis of 115 FLCN mutation carriers from 35 BHD families

(2011) A C Houweling et al.   BRITISH JOURNAL OF CANCER

Molecular Regulation of Lumen Morphogenesis

(2011) Anirban Datta et al.   CURRENT BIOLOGY

Cell-cell connectivity: desmosomes and disease

(2011) Matthew A Brooke et al.   JOURNAL OF PATHOLOGY

The Impact of Germline BHD Mutation on Histological Concordance and Clinical Treatment of Patients With Bilateral Renal Masses and Known Unilateral Oncocytoma

(2011) Ronald S. Boris et al.   JOURNAL OF UROLOGY

mTORC2 Is Required for Proliferation and Survival of TSC2-Null Cells

(2011) E. A. Goncharova et al.   MOLECULAR AND CELLULAR BIOLOGY

Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent

(2011) A. Parkhitko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measurement of Rho-associated kinase (ROCK) activity in humans: Validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil

(2010) Takaki Hata et al.   ATHEROSCLEROSIS

E-cadherin genetic screening and clinico-pathologic characteristics of early onset gastric cancer

(2010) Giovanni Corso et al.   EUROPEAN JOURNAL OF CANCER

A p27kip1-binding Protein, p27RF-Rho, Promotes Cancer Metastasis via Activation of RhoA and RhoC

(2010) Daisuke Hoshino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Absence of the Birt–Hogg–Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

(2010) R S Preston et al.   ONCOGENE

p120ctn and P-Cadherin but Not E-Cadherin Regulate Cell Motility and Invasion of DU145 Prostate Cancer Cells

(2010) Sandra Kümper et al.   PLoS One

Sporadic hybrid oncocytic/chromophobe tumor of the kidney: a clinicopathologic, histomorphologic, immunohistochemical, ultrastructural, and molecular cytogenetic study of 14 cases

(2010) Fredrik Petersson et al.   VIRCHOWS ARCHIV

Mutation analysis of the FLCN gene in Chinese patients with sporadic and familial isolated primary spontaneous pneumothorax

(2009) H-Z Ren et al.   CLINICAL GENETICS

Familial spontaneous pneumothorax and lung cysts due to a Folliculin exon 10 mutation

(2009) S. Sundaram et al.   EUROPEAN RESPIRATORY JOURNAL

Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dubé gene product

(2009) Lu Wang et al.   FEBS LETTERS

Protein p0071, an armadillo plaque protein of adherens junctions, is predominantly expressed in distal renal tubules

(2009) Britta Walter et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The proteins ARVCF and p0071 in renal cell carcinomas and their potential use in the diagnosis of renal tumours

(2009) Britta Walter et al.   HISTOPATHOLOGY

Renal tumour suppressor function of the Birt-Hogg-Dube syndrome gene product folliculin

(2009) V. Hudon et al.   JOURNAL OF MEDICAL GENETICS

Birt-Hogg-Dubé syndrome: diagnosis and management

(2009) Fred H Menko et al.   LANCET ONCOLOGY

The role of the Birt–Hogg–Dubé protein in mTOR activation and renal tumorigenesis

(2009) T R Hartman et al.   ONCOGENE

Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2

(2009) Y. Hasumi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical strain of alveolar type II cells in culture: changes in the transcellular cytokeratin network and adaptations

(2008) Edward Felder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The UOK 257 cell line: a novel model for studies of the human Birt–Hogg–Dubé gene pathway

(2008) Youfeng Yang et al.   CANCER GENETICS AND CYTOGENETICS

Ablation of p120-catenin enhances invasion and metastasis of human lung cancer cells

(2008) Yang Liu et al.   CANCER SCIENCE

Novel mutations in the folliculin gene associated with spontaneous pneumothorax

(2008) B. A. Frohlich et al.   EUROPEAN RESPIRATORY JOURNAL

Identification and characterization of a novel folliculin-interacting protein FNIP2

(2008) Hisashi Hasumi et al.   GENE

Loss of desmocollin 3 in mice leads to epidermal blistering

(2008) J. Chen et al.   JOURNAL OF CELL SCIENCE

Kidney-Targeted Birt-Hogg-Dube Gene Inactivation in a Mouse Model: Erk1/2 and Akt-mTOR Activation, Cell Hyperproliferation, and Polycystic Kidneys

(2008) M. Baba et al.   JNCI-Journal of the National Cancer Institute

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein

(2008) Y Takagi et al.   ONCOGENE

Deficiency of FLCN in Mouse Kidney Led to Development of Polycystic Kidneys and Renal Neoplasia

(2008) Jindong Chen et al.   PLoS One

Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer

(2008) Jian Hong Chu et al.   PROSTATE

Disparate effects of different mutations in plakoglobin on cell mechanical behavior

(2008) Hayden Huang et al.   CELL MOTILITY AND THE CYTOSKELETON