Engineering HIV-1-Resistant T-Cells from Short-Hairpin RNA-Expressing Hematopoietic Stem/Progenitor Cells in Humanized BLT Mice

Hematopoietic-Stem-Cell-Based Gene Therapy for HIV Disease

(2012) Hans-Peter Kiem et al.   Cell Stem Cell

Current progress in the development of RNAi-based therapeutics for HIV-1

(2011) J Zhou et al.   GENE THERAPY

Ex vivo gene therapy for HIV-1 treatment

(2011) L. J. Scherer et al.   HUMAN MOLECULAR GENETICS

Systemic Administration of Combinatorial dsiRNAs via Nanoparticles Efficiently Suppresses HIV-1 Infection in Humanized Mice

(2011) Jiehua Zhou et al.   MOLECULAR THERAPY

A Topical Microbicide Gel Formulation of CCR5 Antagonist Maraviroc Prevents HIV-1 Vaginal Transmission in Humanized RAG-hu Mice

(2011) C. Preston Neff et al.   PLoS One

Engineering HIV-Resistant Human CD4+ T Cells with CXCR4-Specific Zinc-Finger Nucleases

(2011) Craig B. Wilen et al.   PLoS Pathogens

Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation

(2010) K. Allers et al.   BLOOD

The use of cell-delivered gene therapy for the treatment of HIV/AIDS

(2010) Geoff P. Symonds et al.   IMMUNOLOGIC RESEARCH

Inhibition of HIV-1 infection by a unique short hairpin RNA to chemokine receptor 5 delivered into macrophages through hematopoietic progenitor cell transduction

(2010) Min Liang et al.   JOURNAL OF GENE MEDICINE

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

(2010) Nathalia Holt et al.   NATURE BIOTECHNOLOGY

Oral Pre-Exposure Prophylaxis by Anti-Retrovirals Raltegravir and Maraviroc Protects against HIV-1 Vaginal Transmission in a Humanized Mouse Model

(2010) C. Preston Neff et al.   PLoS One

RNA-Based Gene Therapy for HIV with Lentiviral Vector-Modified CD34+ Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma

(2010) D. L. DiGiusto et al.   Science Translational Medicine

A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model

(2009) S. Shimizu et al.   BLOOD

Preintegration HIV-1 Inhibition by a Combination Lentiviral Vector Containing a Chimeric TRIM5α Protein, a CCR5 shRNA, and a TAR Decoy

(2009) Joseph S Anderson et al.   MOLECULAR THERAPY

RNAi-mediated CCR5 Silencing by LFA-1-targeted Nanoparticles Prevents HIV Infection in BLT Mice

(2009) Sang-Soo Kim et al.   MOLECULAR THERAPY

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

96 shRNAs designed for maximal coverage of HIV-1 variants

(2009) Glen Mcintyre et al.   Retrovirology

The Challenge of Finding a Cure for HIV Infection

(2009) D. D. Richman et al.   SCIENCE

Reassessing the Role of APOBEC3G in Human Immunodeficiency Virus Type 1 Infection of Quiescent CD4+ T-Cells

(2009) Masakazu Kamata et al.   PLoS Pathogens

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

Lentiviral Vector Design for Multiple shRNA Expression and Durable HIV-1 Inhibition

(2008) Olivier ter Brake et al.   MOLECULAR THERAPY

Busulfan Produces Efficient Human Cell Engraftment in NOD/LtSz-Scid IL2RγNullMice

(2008) Jun Hayakawa et al.   STEM CELLS

Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance

(2008) Mayur Tamhane et al.   AIDS Research and Therapy