Do Anti-Angiogenic VEGF (VEGFxxxb) Isoforms Exist? A Cautionary Tale

Expression of pro- and anti-angiogenic isoforms of VEGF in the mouse model of oxygen-induced retinopathy

(2011) Min Zhao et al.   EXPERIMENTAL EYE RESEARCH

VEGF121b and VEGF165b are weakly angiogenic isoforms of VEGF-A

(2011) Raúl Catena et al.   Molecular Cancer

Binding to the Extracellular Matrix and Proteolytic Processing: Two Key Mechanisms Regulating Vascular Endothelial Growth Factor Action

(2010) Napoleone Ferrara   MOLECULAR BIOLOGY OF THE CELL

Vascular Endothelial Growth Factor: Much More than an Angiogenesis Factor

(2010) Donald R. Senger   MOLECULAR BIOLOGY OF THE CELL

Cross-Talk between Vascular Endothelial Growth Factor and Matrix Metalloproteinases in the Induction of Neovascularization in Vivo

(2009) Quteba Ebrahem et al.   AMERICAN JOURNAL OF PATHOLOGY

The anti-angiogenic isoforms of VEGF in health and disease

(2009) Yan Qiu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neutralization of Vascular Endothelial Growth Factor Antiangiogenic Isoforms Is More Effective Than Treatment with Proangiogenic Isoforms in Stimulating Vascular Development and Follicle Progression in the Perinatal Rat Ovary1

(2009) Robin A. Artac et al.   BIOLOGY OF REPRODUCTION

VEGF121b, a new member of the VEGF xxx b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo

(2009) E S Rennel et al.   BRITISH JOURNAL OF CANCER

Therapeutic potential of manipulating VEGF splice isoforms in oncology

(2009) Emma S Rennel et al.   Future Oncology

Regulation of Vascular Endothelial Growth Factor (VEGF) Splicing from Pro-angiogenic to Anti-angiogenic Isoforms

(2009) Dawid G. Nowak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy

(2008) A H R Varey et al.   BRITISH JOURNAL OF CANCER

The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice

(2008) E S Rennel et al.   BRITISH JOURNAL OF CANCER

Blood Vessel Maturation and Response to Vascular-Disrupting Therapy in Single Vascular Endothelial Growth Factor-A Isoform-Producing Tumors

(2008) G. M. Tozer et al.   CANCER RESEARCH

Vascular Endothelial Growth Factor (VEGF)-A165b Is a Weak In vitro Agonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity

(2008) H. Kawamura et al.   CANCER RESEARCH

Recombinant human VEGF165b protein is an effective anti-cancer agent in mice

(2008) Emma S. Rennel et al.   EUROPEAN JOURNAL OF CANCER

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

(2008) D. G. Nowak et al.   JOURNAL OF CELL SCIENCE

The Alternatively Spliced Anti-Angiogenic Family of VEGF Isoforms VEGFxxxb in Human Kidney Development

(2008) Heather S. Bevan et al.   NEPHRON PHYSIOLOGY

5-Aza-2′-deoxycytidine increases the expression of anti-angiogenic vascular endothelial growth factor 189b variant in human lung microvascular endothelial cells

(2007) E. Miller-Kasprzak et al.   BIOMEDICINE & PHARMACOTHERAPY

Mammary alveolar development during lactation is inhibited by the endogenous antiangiogenic growth factor isoform, VEGF165b

(2007) Yan Qiu et al.   FASEB JOURNAL