Hierarchical Control on Polyene Macrolide Biosynthesis: PimR Modulates Pimaricin Production via the PAS-LuxR Transcriptional Activator PimM

LAL Regulators SCO0877 and SCO7173 as Pleiotropic Modulators of Phosphate Starvation Response and Actinorhodin Biosynthesis in Streptomyces coelicolor

(2012) Susana M. Guerra et al.   PLoS One

Functional conservation of PAS–LuxR transcriptional regulators in polyene macrolide biosynthesis

(2011) Javier Santos-Aberturas et al.   METABOLIC ENGINEERING

The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis

(2011) Y.-L. Du et al.   MICROBIOLOGY-SGM

Crosstalk between ROS Homeostasis and Secondary Metabolism in S. natalensis ATCC 27448: Modulation of Pimaricin Production by Intracellular ROS

(2011) Tiago Beites et al.   PLoS One

Structure of Cytochrome P450 PimD Suggests Epoxidation of the Polyene Macrolide Pimaricin Occurs via a Hydroperoxoferric Intermediate

(2010) Petrea M. Kells et al.   CHEMISTRY & BIOLOGY

Molecular Control of Polyene Macrolide Biosynthesis

(2010) Javier Santos-Aberturas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two overlapping antiparallel genes encoding the iron regulator DmdR1 and the Adm proteins control sidephore and antibiotic biosynthesis in Streptomyces coelicolor A3(2)

(2009) Sedef Tunca et al.   FEBS Journal

PimT, an amino acid exporter controls polyene production via secretion of the quorum sensing pimaricin-inducer PI-factor in Streptomyces natalensis

(2009) Cláudia M Vicente et al.   Microbial Cell Factories

SanG, a transcriptional activator, controls nikkomycin biosynthesis through binding to the sanN-sanO intergenic region in Streptomyces ansochromogenes

(2009) X. He et al.   MICROBIOLOGY-SGM

polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis

(2009) R. Li et al.   MICROBIOLOGY-SGM

PolY, a transcriptional regulator with ATPase activity, directly activates transcription ofpolRin polyoxin biosynthesis inStreptomyces cacaoi

(2009) Rui Li et al.   MOLECULAR MICROBIOLOGY

Biosynthetic Engineering of Polyene Macrolides Towards Generation of Improved Antifungal and Antiparasitic Agents

(2008) Patrick Caffrey et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Microbial cholesterol oxidases: bioconversion enzymes or signal proteins?

(2008) Jesús F. Aparicio et al.   Molecular BioSystems