Mechanisms of Intramolecular Communication in a Hyperthermophilic Acylaminoacyl Peptidase: A Molecular Dynamics Investigation

Molecular Determinants of Enzyme Cold Adaptation: Comparative Structural and Computational Studies of Cold- and Warm-Adapted Enzymes

(2012) Elena Papaleo et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Structure and Function Relationship in Prolyl Oligopeptidase

(2011) Roos Van Elzen et al.   CNS & Neurological Disorders-Drug Targets

Allosteric Communication in Cysteinyl tRNA Synthetase

(2011) Amit Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic properties of extremophilic subtilisin-like serine-proteases

(2011) Matteo Tiberti et al.   JOURNAL OF STRUCTURAL BIOLOGY

The Contribution of Coevolving Residues to the Stability of KDO8P Synthase

(2011) Sharon H. Ackerman et al.   PLoS One

Molecular Dynamics of Mesophilic-Like Mutants of a Cold-Adapted Enzyme: Insights into Distal Effects Induced by the Mutations

(2011) Elena Papaleo et al.   PLoS One

Identification of functional motions in the adenylate kinase (ADK) protein family by computational hybrid approaches

(2011) Dagoberto Armenta-Medina et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

“Fluctuograms” Reveal the Intermittent Intra-Protein Communication in Subtilisin Carlsberg and Correlate Mechanical Coupling with Co-Evolution

(2011) Jordi Silvestre-Ryan et al.   PLoS Computational Biology

Functional Modes and Residue Flexibility Control the Anisotropic Response of Guanylate Kinase to Mechanical Stress

(2010) Sophie Sacquin-Mora et al.   BIOPHYSICAL JOURNAL

An Unusual Hydrophobic Core Confers Extreme Flexibility to HEAT Repeat Proteins

(2010) Christian Kappel et al.   BIOPHYSICAL JOURNAL

Choreographing an enzyme's dance

(2010) Janice Villali et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Coupled motions in enzyme catalysis

(2010) Vishal C Nashine et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Enzyme dynamics point to stepwise conformational selection in catalysis

(2010) Buyong Ma et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Unraveling evolutionary constraints: A heterogeneous conservation in dynamics of the titin Ig domains

(2010) Suryani Lukman et al.   FEBS LETTERS

Structure and Catalysis of Acylaminoacyl Peptidase

(2010) Veronika Harmat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wordom: A user-friendly program for the analysis of molecular structures, trajectories, and free energy surfaces

(2010) Michele Seeber et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Protein stability and enzyme activity at extreme biological temperatures

(2010) Georges Feller   JOURNAL OF PHYSICS-CONDENSED MATTER

Refinement of Ensembles Describing Unstructured Proteins Using NMR Residual Dipolar Couplings

(2010) Santi Esteban-Martín et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Studies on the specificity of acetylaminoacylpeptide hydrolase

(2010) Charles W. Sokolik et al.   PROTEIN SCIENCE

On the Conservation of the Slow Conformational Dynamics within the Amino Acid Kinase Family: NAGK the Paradigm

(2010) Enrique Marcos et al.   PLoS Computational Biology

The molecular basis of the effect of temperature on enzyme activity

(2009) Roy M. Daniel et al.   BIOCHEMICAL JOURNAL

FlexServ: an integrated tool for the analysis of protein flexibility

(2009) J. Camps et al.   BIOINFORMATICS

Intra and Inter-Molecular Communications Through Protein Structure Network

(2009) Saraswathi Vishveshwara et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

A new side opening on prolyl oligopeptidase revealed by electron microscopy

(2009) Teresa Tarragó et al.   FEBS LETTERS

Toward a Unified Representation of Protein Structural Dynamics in Solution

(2009) Phineus R. L. Markwick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conservation of Side-Chain Dynamics Within a Protein Family

(2009) Anthony B. Law et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A perturbative view of protein structural variation

(2009) Julián Echave et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Effects of bundling on the properties of the SPC water model

(2009) Marc Fuhrmans et al.   THEORETICAL CHEMISTRY ACCOUNTS

Modeling Signal Propagation Mechanisms and Ligand-Based Conformational Dynamics of the Hsp90 Molecular Chaperone Full-Length Dimer

(2009) Giulia Morra et al.   PLoS Computational Biology

The conserved N-terminal helix of acylpeptide hydrolase from archaeon Aeropyrum pernix K1 is important for its hyperthermophilic activity

(2008) Zuoming Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Glu88 in the non-catalytic domain of acylpeptide hydrolase plays dual roles: Charge neutralization for enzymatic activity and formation of salt bridge for thermodynamic stability

(2008) Guangyu Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

ProtorP: a protein-protein interaction analysis server

(2008) C. Reynolds et al.   BIOINFORMATICS

Molecular simulations of protein dynamics: new windows on mechanisms in biology

(2008) Guy G Dodson et al.   EMBO REPORTS

Evolutionary conservation of protein vibrational dynamics

(2008) Sandra Maguid et al.   GENE

Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase

(2008) András L. Kiss et al.   JOURNAL OF STRUCTURAL BIOLOGY