Development of a Multi-Step Leukemogenesis Model of MLL-Rearranged Leukemia Using Humanized Mice
Published 2012 View Full Article
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Title
Development of a Multi-Step Leukemogenesis Model of MLL-Rearranged Leukemia Using Humanized Mice
Authors
Keywords
Leukemias, Mouse models, Spleen, Stem cell transplantation, Acute myeloid leukemia, Leukemia cells, Liver transplantation, Oncogenes
Journal
PLoS One
Volume 7, Issue 6, Pages e37892
Publisher
Public Library of Science (PLoS)
Online
2012-06-21
DOI
10.1371/journal.pone.0037892
References
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Note: Only part of the references are listed.- Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia
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