BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells

Repression of BMI1 in normal and leukemic human CD34+ cells impairs self-renewal and induces apoptosis

(2009) A. Rizo et al.   BLOOD

Bmi1 regulates mitochondrial function and the DNA damage response pathway

(2009) Jie Liu et al.   NATURE

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

(2009) Chen Zhao et al.   NATURE

The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene

(2008) P.-Y. Wang et al.   BLOOD

Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

(2008) Christine Dierks et al.   CANCER CELL

Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia

(2008) Junping Wei et al.   CANCER CELL

Mucin1 expression is enriched in the human stem cell fraction of cord blood and is upregulated in majority of the AML cases

(2008) Szabolcs Fatrai et al.   EXPERIMENTAL HEMATOLOGY

Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL

(2008) C. G. Mullighan et al.   GENES & DEVELOPMENT

Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf

(2008) R. A.J. Signer et al.   GENES & DEVELOPMENT

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

(2008) Charles G. Mullighan et al.   NATURE