Nitroxyl (HNO) Stimulates Soluble Guanylyl Cyclase to Suppress Cardiomyocyte Hypertrophy and Superoxide Generation

Playing with Cardiac “Redox Switches”: The “HNO Way” to Modulate Cardiac Function

(2011) Carlo G. Tocchetti et al.   ANTIOXIDANTS & REDOX SIGNALING

β1-Integrin is up-regulated via Rac1-dependent reactive oxygen species as part of the hypertrophic cardiomyocyte response

(2011) Stéphanie P. Häuselmann et al.   FREE RADICAL BIOLOGY AND MEDICINE

mTOR mediates RhoA-dependent leptin-induced cardiomyocyte hypertrophy

(2011) Asad Zeidan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Chronic Administration of the HNO Donor Angeli's Salt Does Not Lead to Tolerance, Cross-Tolerance, or Endothelial Dysfunction: Comparison with GTN and DEA/NO

(2010) Jennifer C. Irvine et al.   ANTIOXIDANTS & REDOX SIGNALING

Nitroxyl (HNO) as a Vasoprotective Signaling Molecule

(2010) Michelle L. Bullen et al.   ANTIOXIDANTS & REDOX SIGNALING

Myocardial oxidative stress contributes to transgenic β2-adrenoceptor activation-induced cardiomyopathy and heart failure

(2010) Q Xu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nitroxyl Activates SERCA in Cardiac Myocytes via Glutathiolation of Cysteine 674

(2009) Steve Lancel et al.   CIRCULATION RESEARCH

B-Type Natriuretic Peptide: Endogenous Regulator of Myocardial Structure, Biomarker and Therapeutic Target

(2009) Rebecca Ritchie et al.   CURRENT MOLECULAR MEDICINE

The Effects of Nitroxyl (HNO) on Soluble Guanylate Cyclase Activity

(2009) Thomas W. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms Underlying Activation of Soluble Guanylate Cyclase by the Nitroxyl Donor Angeli's Salt

(2009) A. Zeller et al.   MOLECULAR PHARMACOLOGY

Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO• and beyond

(2009) Rebecca H. Ritchie et al.   PHARMACOLOGY & THERAPEUTICS

Phospholamban Thiols Play a Central Role in Activation of the Cardiac Muscle Sarcoplasmic Reticulum Calcium Pump by Nitroxyl†

(2008) Jeffrey P. Froehlich et al.   BIOCHEMISTRY

Nitroxyl (HNO): the Cinderella of the nitric oxide story

(2008) Jennifer C. Irvine et al.   TRENDS IN PHARMACOLOGICAL SCIENCES