Small Interfering RNA Targeted to IGF-IR Delays Tumor Growth and Induces Proinflammatory Cytokines in a Mouse Breast Cancer Model

TNFα Cooperates with IFN-γ to Repress Bcl-xL Expression to Sensitize Metastatic Colon Carcinoma Cells to TRAIL-mediated Apoptosis

(2011) Feiyan Liu et al.   PLoS One

Antisense anti IGF-I cellular therapy of malignant tumours: Immune response in cancer patients

(2010) J. Trojan et al.   BIOMEDICINE & PHARMACOTHERAPY

Cancer and Inflammation: Implications for Pharmacology and Therapeutics

(2010) F Balkwill et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Sequence-specific targeting of IGF-I and IGF-IR genes by camptothecins

(2010) Kahina Oussedik et al.   FASEB JOURNAL

Synthetic siRNA targeting the breakpoint of EWS/Fli-1 inhibits growth of Ewing sarcoma xenografts in a mouse model

(2010) Iori Takigami et al.   INTERNATIONAL JOURNAL OF CANCER

Rational Design of Immunostimulatory siRNAs

(2010) Michael P Gantier et al.   MOLECULAR THERAPY

Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay

(2010) Fernando Pastor et al.   NATURE

Insulin-Like Growth Factor-I Regulation of Immune Function: A Potential Therapeutic Target in Autoimmune Diseases?

(2010) T. J. Smith   PHARMACOLOGICAL REVIEWS

Transforming Growth Factor- -Stimulated Clone-22 Is an Androgen-Regulated Gene That Enhances Apoptosis in Prostate Cancer following Insulin-Like Growth Factor-I Receptor Inhibition

(2009) C. C.T. Sprenger et al.   CLINICAL CANCER RESEARCH

The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer

(2009) Claudia Lanari et al.   ENDOCRINE-RELATED CANCER

Validation of the type 1 insulin-like growth factor receptor as a therapeutic target in renal cancer

(2009) J. S.P. Yuen et al.   MOLECULAR CANCER THERAPEUTICS

Tumor necrosis factor deficiency inhibits mammary tumorigenesis and a tumor necrosis factor neutralizing antibody decreases mammary tumor growth in neu/erbB2 transgenic mice

(2009) M. A. Warren et al.   MOLECULAR CANCER THERAPEUTICS

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

(2009) Aimee L. Jackson et al.   NATURE REVIEWS DRUG DISCOVERY

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

(2009) A Gualberto et al.   ONCOGENE

Regulation of IGF-I function by proinflammatory cytokines: At the interface of immunology and endocrinology

(2008) Jason C. O’Connor et al.   CELLULAR IMMUNOLOGY

Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer

(2008) John SP Yuen et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Role of Endocrine Insulin-Like Growth Factor-I and Insulin in Breast Cancer

(2008) Danielle Lann et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Activation of Stat3 by Heregulin/ErbB-2 through the Co-Option of Progesterone Receptor Signaling Drives Breast Cancer Growth

(2008) C. J. Proietti et al.   MOLECULAR AND CELLULAR BIOLOGY

TNFα acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-κB-dependent pathways

(2007) Martín A. Rivas et al.   EXPERIMENTAL CELL RESEARCH