Amyloid-Like Fibril Formation by PolyQ Proteins: A Critical Balance between the PolyQ Length and the Constraints Imposed by the Host Protein

Location Trumps Length: Polyglutamine-Mediated Changes in Folding and Aggregation of a Host Protein

(2011) Matthew D. Tobelmann et al.   BIOPHYSICAL JOURNAL

The Rate of PolyQ-Mediated Aggregation Is Dramatically Affected by the Number and Location of Surrounding Domains

(2011) Amy L. Robertson et al.   JOURNAL OF MOLECULAR BIOLOGY

Flanking domain stability modulates the aggregation kinetics of a polyglutamine disease protein

(2011) Helen M. Saunders et al.   PROTEIN SCIENCE

Folding of Class A β-Lactamases Is Rate-Limited by Peptide Bond Isomerization and Occurs via Parallel Pathways

(2010) Julie Vandenameele et al.   BIOCHEMISTRY

Towards the Treatment of Polyglutamine Diseases: The Modulatory Role of Protein Context

(2010) A. L. Robertson et al.   CURRENT MEDICINAL CHEMISTRY

Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool

(2010) Maya A. Olshina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Non-Core Regions of Human Lysozyme Amyloid Fibrils Influence Cytotoxicity

(2010) Maria F. Mossuto et al.   JOURNAL OF MOLECULAR BIOLOGY

Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences

(2010) Vinal V. Lakhani et al.   PLoS Computational Biology

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

(2009) Ashwani K Thakur et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Secondary Structure of Huntingtin Amino-Terminal Region

(2009) Mee Whi Kim et al.   STRUCTURE

The Structural Impact of a Polyglutamine Tract Is Location-Dependent

(2008) Amy L. Robertson et al.   BIOPHYSICAL JOURNAL

The Zinc Center Influences the Redox and Thermodynamic Properties of Escherichia coli Thioredoxin 2

(2008) Hayat El Hajjaji et al.   JOURNAL OF MOLECULAR BIOLOGY

Rapid and easy development of versatile tools to study protein/ligand interactions

(2008) M. Vandevenne et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A strategy for generating polyglutamine 'length libraries' in model host proteins

(2008) M. D. Tobelmann et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Polyglutamine neurodegeneration: protein misfolding revisited

(2008) Aislinn J. Williams et al.   TRENDS IN NEUROSCIENCES

Single-domain antibody fragments with high conformational stability

(2002) Mireille Dumoulin et al.   PROTEIN SCIENCE