Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences
Published 2010 View Full Article
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Title
Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences
Authors
Keywords
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Journal
PLoS Computational Biology
Volume 6, Issue 4, Pages e1000772
Publisher
Public Library of Science (PLoS)
Online
2010-04-30
DOI
10.1371/journal.pcbi.1000772
References
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Related references
Note: Only part of the references are listed.- Thermodynamics of β-Sheet Formation in Polyglutamine
- (2009) Andreas Vitalis et al. BIOPHYSICAL JOURNAL
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- (2009) Keizo Sugaya et al. Molecular Neurodegeneration
- The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation
- (2009) Stephen Tam et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism
- (2009) Ashwani K Thakur et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity
- (2009) Y. Nekooki-Machida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins
- (2009) H. M. Saunders et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Secondary Structure of Huntingtin Amino-Terminal Region
- (2009) Mee Whi Kim et al. STRUCTURE
- Huntington’s disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases
- (2008) Ray Truant et al. FEBS Journal
- Probing protein aggregation using discrete molecular dynamics
- (2008) Shantanu Sharma Frontiers in Bioscience-Landmark
- Folding of polyglutamine chains
- (2008) Manan Chopra et al. JOURNAL OF CHEMICAL PHYSICS
- Atomistic Simulations of the Effects of Polyglutamine Chain Length and Solvent Quality on Conformational Equilibria and Spontaneous Homodimerization
- (2008) Andreas Vitalis et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural Properties of Polyglutamine Aggregates Investigated via Molecular Dynamics Simulations
- (2008) Giulia Rossetti et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation
- (2008) F. Ding et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ab Initio Folding of Proteins with All-Atom Discrete Molecular Dynamics
- (2008) Feng Ding et al. STRUCTURE
- Protein folding: Then and now
- (2007) Yiwen Chen et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Molecular dynamics simulation study on the structural stabilities of polyglutamine peptides
- (2007) Hajime Ogawa et al. COMPUTATIONAL BIOLOGY AND CHEMISTRY
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